Lepper ER - Search Results

1

Prediction of irinotecan pharmacokinetics by use of cytochrome P450 3A4 phenotyping probes.

Mathijssen RH, de Jong FA, van Schaik RH, Lepper ER, Friberg LE, Rietveld T, de Bruijn P, Graveland WJ, Figg WD, Verweij J, Sparreboom A. Mathijssen RH, et al. Among authors: lepper er. J Natl Cancer Inst. 2004 Nov 3;96(21):1585-92. doi: 10.1093/jnci/djh298. J Natl Cancer Inst. 2004. PMID: 15523087

2

Effect of common CYP3A4 and CYP3A5 variants on the pharmacokinetics of the cytochrome P450 3A phenotyping probe midazolam in cancer patients.

Lepper ER, Baker SD, Permenter M, Ries N, van Schaik RH, Schenk PW, Price DK, Ahn D, Smith NF, Cusatis G, Ingersoll RG, Bates SE, Mathijssen RH, Verweij J, Figg WD, Sparreboom A. Lepper ER, et al. Clin Cancer Res. 2005 Oct 15;11(20):7398-404. doi: 10.1158/1078-0432.CCR-05-0520. Clin Cancer Res. 2005. PMID: 16243813 Clinical Trial.

3

Liquid-chromatographic determination of erlotinib (OSI-774), an epidermal growth factor receptor tyrosine kinase inhibitor.

Lepper ER, Swain SM, Tan AR, Figg WD, Sparreboom A. Lepper ER, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Oct 25;796(1):181-8. doi: 10.1016/j.jchromb.2003.08.015. J Chromatogr B Analyt Technol Biomed Life Sci. 2003. PMID: 14552829

4

Determination of CC-5013, an analogue of thalidomide, in human plasma by liquid chromatography-mass spectrometry.

Tohnya TM, Hwang K, Lepper ER, Fine HA, Dahut WL, Venitz J, Sparreboom A, Figg WD. Tohnya TM, et al. Among authors: lepper er. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Nov 25;811(2):135-41. doi: 10.1016/j.jchromb.2004.08.022. J Chromatogr B Analyt Technol Biomed Life Sci. 2004. PMID: 15522712

5

Determination of midazolam in human plasma by liquid chromatography with mass-spectrometric detection.

Lepper ER, Hicks JK, Verweij J, Zhai S, Figg WD, Sparreboom A. Lepper ER, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Jul 5;806(2):305-10. doi: 10.1016/j.jchromb.2004.04.003. J Chromatogr B Analyt Technol Biomed Life Sci. 2004. PMID: 15171944

6

Importance of the stress kinase p38alpha in mediating the direct cytotoxic effects of the thalidomide analogue, CPS49, in cancer cells and endothelial cells.

Warfel NA, Lepper ER, Zhang C, Figg WD, Dennis PA. Warfel NA, et al. Among authors: lepper er. Clin Cancer Res. 2006 Jun 1;12(11 Pt 1):3502-9. doi: 10.1158/1078-0432.CCR-05-1837. Clin Cancer Res. 2006. PMID: 16740776

7

Determination of 2-methoxyestradiol in human plasma, using liquid chromatography/tandem mass spectrometry.

Lakhani NJ, Lepper ER, Sparreboom A, Dahut WL, Venitz J, Figg WD. Lakhani NJ, et al. Among authors: lepper er. Rapid Commun Mass Spectrom. 2005;19(9):1176-82. doi: 10.1002/rcm.1902. Rapid Commun Mass Spectrom. 2005. PMID: 15818726

8

Mechanisms of resistance to anticancer drugs: the role of the polymorphic ABC transporters ABCB1 and ABCG2.

Lepper ER, Nooter K, Verweij J, Acharya MR, Figg WD, Sparreboom A. Lepper ER, et al. Pharmacogenomics. 2005 Mar;6(2):115-38. doi: 10.1517/14622416.6.2.115. Pharmacogenomics. 2005. PMID: 15882131 Review.

9

Evaluation of biologic end points and pharmacokinetics in patients with metastatic breast cancer after treatment with erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor.

Tan AR, Yang X, Hewitt SM, Berman A, Lepper ER, Sparreboom A, Parr AL, Figg WD, Chow C, Steinberg SM, Bacharach SL, Whatley M, Carrasquillo JA, Brahim JS, Ettenberg SA, Lipkowitz S, Swain SM. Tan AR, et al. Among authors: lepper er. J Clin Oncol. 2004 Aug 1;22(15):3080-90. doi: 10.1200/JCO.2004.08.189. J Clin Oncol. 2004. PMID: 15284258

10

Thalidomide metabolism and hydrolysis: mechanisms and implications.

Lepper ER, Smith NF, Cox MC, Scripture CD, Figg WD. Lepper ER, et al. Curr Drug Metab. 2006 Aug;7(6):677-85. doi: 10.2174/138920006778017777. Curr Drug Metab. 2006. PMID: 16918319 Review.

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