Van Remmen H - Search Results

1

CuZnSOD deficiency leads to persistent and widespread oxidative damage and hepatocarcinogenesis later in life.

Elchuri S, Oberley TD, Qi W, Eisenstein RS, Jackson Roberts L, Van Remmen H, Epstein CJ, Huang TT. Elchuri S, et al. Among authors: van remmen h. Oncogene. 2005 Jan 13;24(3):367-80. doi: 10.1038/sj.onc.1208207. Oncogene. 2005. PMID: 15531919

2

Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging.

Mansouri A, Muller FL, Liu Y, Ng R, Faulkner J, Hamilton M, Richardson A, Huang TT, Epstein CJ, Van Remmen H. Mansouri A, et al. Among authors: van remmen h. Mech Ageing Dev. 2006 Mar;127(3):298-306. doi: 10.1016/j.mad.2005.11.004. Epub 2006 Jan 6. Mech Ageing Dev. 2006. PMID: 16405961

3

Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging.

Van Remmen H, Ikeno Y, Hamilton M, Pahlavani M, Wolf N, Thorpe SR, Alderson NL, Baynes JW, Epstein CJ, Huang TT, Nelson J, Strong R, Richardson A. Van Remmen H, et al. Physiol Genomics. 2003 Dec 16;16(1):29-37. doi: 10.1152/physiolgenomics.00122.2003. Physiol Genomics. 2003. PMID: 14679299

4

Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress.

Van Remmen H, Qi W, Sabia M, Freeman G, Estlack L, Yang H, Mao Guo Z, Huang TT, Strong R, Lee S, Epstein CJ, Richardson A. Van Remmen H, et al. Free Radic Biol Med. 2004 Jun 15;36(12):1625-34. doi: 10.1016/j.freeradbiomed.2004.03.016. Free Radic Biol Med. 2004. PMID: 15182862

5

Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy.

Muller FL, Song W, Liu Y, Chaudhuri A, Pieke-Dahl S, Strong R, Huang TT, Epstein CJ, Roberts LJ 2nd, Csete M, Faulkner JA, Van Remmen H. Muller FL, et al. Among authors: van remmen h. Free Radic Biol Med. 2006 Jun 1;40(11):1993-2004. doi: 10.1016/j.freeradbiomed.2006.01.036. Epub 2006 Feb 17. Free Radic Biol Med. 2006. PMID: 16716900

6

Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity.

Zhang Y, Ikeno Y, Qi W, Chaudhuri A, Li Y, Bokov A, Thorpe SR, Baynes JW, Epstein C, Richardson A, Van Remmen H. Zhang Y, et al. Among authors: van remmen h. J Gerontol A Biol Sci Med Sci. 2009 Dec;64(12):1212-20. doi: 10.1093/gerona/glp132. Epub 2009 Sep 23. J Gerontol A Biol Sci Med Sci. 2009. PMID: 19776219 Free PMC article.

7

Increased oxidative damage is correlated to altered mitochondrial function in heterozygous manganese superoxide dismutase knockout mice.

Williams MD, Van Remmen H, Conrad CC, Huang TT, Epstein CJ, Richardson A. Williams MD, et al. Among authors: van remmen h. J Biol Chem. 1998 Oct 23;273(43):28510-5. doi: 10.1074/jbc.273.43.28510. J Biol Chem. 1998. PMID: 9774481 Free article.

8

The in vivo gene expression signature of oxidative stress.

Han ES, Muller FL, Pérez VI, Qi W, Liang H, Xi L, Fu C, Doyle E, Hickey M, Cornell J, Epstein CJ, Roberts LJ, Van Remmen H, Richardson A. Han ES, et al. Among authors: van remmen h. Physiol Genomics. 2008 Jun 12;34(1):112-26. doi: 10.1152/physiolgenomics.00239.2007. Epub 2008 Apr 29. Physiol Genomics. 2008. PMID: 18445702 Free PMC article.

9

Overexpression of Mn superoxide dismutase does not increase life span in mice.

Jang YC, Pérez VI, Song W, Lustgarten MS, Salmon AB, Mele J, Qi W, Liu Y, Liang H, Chaudhuri A, Ikeno Y, Epstein CJ, Van Remmen H, Richardson A. Jang YC, et al. Among authors: van remmen h. J Gerontol A Biol Sci Med Sci. 2009 Nov;64(11):1114-25. doi: 10.1093/gerona/glp100. Epub 2009 Jul 24. J Gerontol A Biol Sci Med Sci. 2009. PMID: 19633237 Free PMC article.

10

Knockout mice heterozygous for Sod2 show alterations in cardiac mitochondrial function and apoptosis.

Van Remmen H, Williams MD, Guo Z, Estlack L, Yang H, Carlson EJ, Epstein CJ, Huang TT, Richardson A. Van Remmen H, et al. Am J Physiol Heart Circ Physiol. 2001 Sep;281(3):H1422-32. doi: 10.1152/ajpheart.2001.281.3.H1422. Am J Physiol Heart Circ Physiol. 2001. PMID: 11514315 Free article.

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