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Mouse model carrying H222P-Lmna mutation develops muscular dystrophy and dilated cardiomyopathy similar to human striated muscle laminopathies.
Arimura T, Helbling-Leclerc A, Massart C, Varnous S, Niel F, Lacène E, Fromes Y, Toussaint M, Mura AM, Keller DI, Amthor H, Isnard R, Malissen M, Schwartz K, Bonne G. Arimura T, et al. Among authors: varnous s. Hum Mol Genet. 2005 Jan 1;14(1):155-69. doi: 10.1093/hmg/ddi017. Epub 2004 Nov 17. Hum Mol Genet. 2005. PMID: 15548545
Clinical course of arrhythmogenic right ventricular cardiomyopathy with end-stage heart failure and outcome after heart transplantation.
Petruescu L, Lebreton G, Coutance G, Maupain C, Fressart V, Badenco N, Waintraub X, Duthoit G, Laredo M, Himbert C, Hidden-Lucet F, Leprince P, Varnous S, Gandjbakhch E. Petruescu L, et al. Among authors: varnous s. Arch Cardiovasc Dis. 2023 Jan;116(1):9-17. doi: 10.1016/j.acvd.2022.10.005. Epub 2022 Dec 9. Arch Cardiovasc Dis. 2023. PMID: 36609000 Free article.
Sudden cardiac death after heart transplantation: a population-based study.
Bonnet G, Coutance G, Aubert O, Waldmann V, Raynaud M, Asselin A, Bories MC, Guillemain R, Bruneval P, Varnous S, Leprince P, Achouch P, Marijon E, Loupy A, Jouven X. Bonnet G, et al. Among authors: varnous s. Europace. 2023 May 19;25(5):euad126. doi: 10.1093/europace/euad126. Europace. 2023. PMID: 37208303 Free PMC article.
Heterozygous LmnadelK32 mice develop dilated cardiomyopathy through a combined pathomechanism of haploinsufficiency and peptide toxicity.
Cattin ME, Bertrand AT, Schlossarek S, Le Bihan MC, Skov Jensen S, Neuber C, Crocini C, Maron S, Lainé J, Mougenot N, Varnous S, Fromes Y, Hansen A, Eschenhagen T, Decostre V, Carrier L, Bonne G. Cattin ME, et al. Among authors: varnous s. Hum Mol Genet. 2013 Aug 1;22(15):3152-64. doi: 10.1093/hmg/ddt172. Epub 2013 Apr 10. Hum Mol Genet. 2013. PMID: 23575224 Free article.
Effect of intracoronary administration of AAV1/SERCA2a on ventricular remodelling in patients with advanced systolic heart failure: results from the AGENT-HF randomized phase 2 trial.
Hulot JS, Salem JE, Redheuil A, Collet JP, Varnous S, Jourdain P, Logeart D, Gandjbakhch E, Bernard C, Hatem SN, Isnard R, Cluzel P, Le Feuvre C, Leprince P, Hammoudi N, Lemoine FM, Klatzmann D, Vicaut E, Komajda M, Montalescot G, Lompré AM, Hajjar RJ; AGENT-HF Investigators. Hulot JS, et al. Among authors: varnous s. Eur J Heart Fail. 2017 Nov;19(11):1534-1541. doi: 10.1002/ejhf.826. Epub 2017 Apr 10. Eur J Heart Fail. 2017. PMID: 28393439 Free article. Clinical Trial.
Desmosomal cadherins are decreased in explanted arrhythmogenic right ventricular dysplasia/cardiomyopathy patient hearts.
Vite A, Gandjbakhch E, Prost C, Fressart V, Fouret P, Neyroud N, Gary F, Donal E, Varnous S, Fontaine G, Fornes P, Hidden-Lucet F, Komajda M, Charron P, Villard E. Vite A, et al. Among authors: varnous s. PLoS One. 2013 Sep 23;8(9):e75082. doi: 10.1371/journal.pone.0075082. eCollection 2013. PLoS One. 2013. PMID: 24086444 Free PMC article.
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