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Modulation of synaptic transmission by the BCL-2 family protein BCL-xL.
Jonas EA, Hoit D, Hickman JA, Brandt TA, Polster BM, Fannjiang Y, McCarthy E, Montanez MK, Hardwick JM, Kaczmarek LK. Jonas EA, et al. Among authors: hardwick jm. J Neurosci. 2003 Sep 10;23(23):8423-31. doi: 10.1523/JNEUROSCI.23-23-08423.2003. J Neurosci. 2003. PMID: 12968005 Free PMC article.
Proapoptotic N-truncated BCL-xL protein activates endogenous mitochondrial channels in living synaptic terminals.
Jonas EA, Hickman JA, Chachar M, Polster BM, Brandt TA, Fannjiang Y, Ivanovska I, Basañez G, Kinnally KW, Zimmerberg J, Hardwick JM, Kaczmarek LK. Jonas EA, et al. Among authors: hardwick jm. Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13590-5. doi: 10.1073/pnas.0401372101. Epub 2004 Sep 1. Proc Natl Acad Sci U S A. 2004. PMID: 15342906 Free PMC article.
Bcl-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons.
Li H, Chen Y, Jones AF, Sanger RH, Collis LP, Flannery R, McNay EC, Yu T, Schwarzenbacher R, Bossy B, Bossy-Wetzel E, Bennett MV, Pypaert M, Hickman JA, Smith PJ, Hardwick JM, Jonas EA. Li H, et al. Among authors: hardwick jm. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2169-74. doi: 10.1073/pnas.0711647105. Epub 2008 Feb 4. Proc Natl Acad Sci U S A. 2008. PMID: 18250306 Free PMC article.
Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase.
Alavian KN, Li H, Collis L, Bonanni L, Zeng L, Sacchetti S, Lazrove E, Nabili P, Flaherty B, Graham M, Chen Y, Messerli SM, Mariggio MA, Rahner C, McNay E, Shore GC, Smith PJ, Hardwick JM, Jonas EA. Alavian KN, et al. Among authors: hardwick jm. Nat Cell Biol. 2011 Sep 18;13(10):1224-33. doi: 10.1038/ncb2330. Nat Cell Biol. 2011. PMID: 21926988 Free PMC article.
Bcl-xL regulates mitochondrial energetics by stabilizing the inner membrane potential.
Chen YB, Aon MA, Hsu YT, Soane L, Teng X, McCaffery JM, Cheng WC, Qi B, Li H, Alavian KN, Dayhoff-Brannigan M, Zou S, Pineda FJ, O'Rourke B, Ko YH, Pedersen PL, Kaczmarek LK, Jonas EA, Hardwick JM. Chen YB, et al. Among authors: hardwick jm. J Cell Biol. 2011 Oct 17;195(2):263-76. doi: 10.1083/jcb.201108059. Epub 2011 Oct 10. J Cell Biol. 2011. PMID: 21987637 Free PMC article.
BAK alters neuronal excitability and can switch from anti- to pro-death function during postnatal development.
Fannjiang Y, Kim CH, Huganir RL, Zou S, Lindsten T, Thompson CB, Mito T, Traystman RJ, Larsen T, Griffin DE, Mandir AS, Dawson TM, Dike S, Sappington AL, Kerr DA, Jonas EA, Kaczmarek LK, Hardwick JM. Fannjiang Y, et al. Among authors: hardwick jm. Dev Cell. 2003 Apr;4(4):575-85. doi: 10.1016/s1534-5807(03)00091-1. Dev Cell. 2003. PMID: 12689595 Free article.
Zinc-dependent multi-conductance channel activity in mitochondria isolated from ischemic brain.
Bonanni L, Chachar M, Jover-Mengual T, Li H, Jones A, Yokota H, Ofengeim D, Flannery RJ, Miyawaki T, Cho CH, Polster BM, Pypaert M, Hardwick JM, Sensi SL, Zukin RS, Jonas EA. Bonanni L, et al. Among authors: hardwick jm. J Neurosci. 2006 Jun 21;26(25):6851-62. doi: 10.1523/JNEUROSCI.5444-05.2006. J Neurosci. 2006. PMID: 16793892 Free PMC article.
158 results