Simmet T - Search Results

1

Inhibition of IkappaB kinase activity by acetyl-boswellic acids promotes apoptosis in androgen-independent PC-3 prostate cancer cells in vitro and in vivo.

Syrovets T, Gschwend JE, Büchele B, Laumonnier Y, Zugmaier W, Genze F, Simmet T. Syrovets T, et al. Among authors: simmet t. J Biol Chem. 2005 Feb 18;280(7):6170-80. doi: 10.1074/jbc.M409477200. Epub 2004 Dec 2. J Biol Chem. 2005. PMID: 15576374 Free article.

2

The serine protease plasmin triggers expression of MCP-1 and CD40 in human primary monocytes via activation of p38 MAPK and janus kinase (JAK)/STAT signaling pathways.

Burysek L, Syrovets T, Simmet T. Burysek L, et al. Among authors: simmet t. J Biol Chem. 2002 Sep 6;277(36):33509-17. doi: 10.1074/jbc.M201941200. Epub 2002 Jul 1. J Biol Chem. 2002. PMID: 12093796 Free article.

3

Acetyl-boswellic acids inhibit lipopolysaccharide-mediated TNF-alpha induction in monocytes by direct interaction with IkappaB kinases.

Syrovets T, Büchele B, Krauss C, Laumonnier Y, Simmet T. Syrovets T, et al. Among authors: simmet t. J Immunol. 2005 Jan 1;174(1):498-506. doi: 10.4049/jimmunol.174.1.498. J Immunol. 2005. PMID: 15611276

4

High-performance liquid chromatographic determination of acetyl-11-keto-alpha-boswellic acid, a novel pentacyclic triterpenoid, in plasma using a fluorinated stationary phase and photodiode array detection: application in pharmacokinetic studies.

Büchele B, Zugmaier W, Genze F, Simmet T. Büchele B, et al. Among authors: simmet t. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Dec 27;829(1-2):144-8. doi: 10.1016/j.jchromb.2005.09.043. Epub 2005 Nov 2. J Chromatogr B Analyt Technol Biomed Life Sci. 2005. PMID: 16266833

5

Characterization of 3alpha-acetyl-11-keto-alpha-boswellic acid, a pentacyclic triterpenoid inducing apoptosis in vitro and in vivo.

Büchele B, Zugmaier W, Estrada A, Genze F, Syrovets T, Paetz C, Schneider B, Simmet T. Büchele B, et al. Among authors: simmet t. Planta Med. 2006 Nov;72(14):1285-9. doi: 10.1055/s-2006-951680. Epub 2006 Oct 4. Planta Med. 2006. PMID: 17022003

6

Tirucallic acids are novel pleckstrin homology domain-dependent Akt inhibitors inducing apoptosis in prostate cancer cells.

Estrada AC, Syrovets T, Pitterle K, Lunov O, Büchele B, Schimana-Pfeifer J, Schmidt T, Morad SA, Simmet T. Estrada AC, et al. Among authors: simmet t. Mol Pharmacol. 2010 Mar;77(3):378-87. doi: 10.1124/mol.109.060475. Epub 2009 Dec 16. Mol Pharmacol. 2010. PMID: 20018812

7

A novel semisynthetic inhibitor of the FRB domain of mammalian target of rapamycin blocks proliferation and triggers apoptosis in chemoresistant prostate cancer cells.

Morad SA, Schmid M, Büchele B, Siehl HU, El Gafaary M, Lunov O, Syrovets T, Simmet T. Morad SA, et al. Among authors: simmet t. Mol Pharmacol. 2013 Feb;83(2):531-41. doi: 10.1124/mol.112.081349. Epub 2012 Dec 3. Mol Pharmacol. 2013. PMID: 23208958

8

Novel aspects and new roles for the serine protease plasmin.

Syrovets T, Simmet T. Syrovets T, et al. Among authors: simmet t. Cell Mol Life Sci. 2004 Apr;61(7-8):873-85. doi: 10.1007/s00018-003-3348-5. Cell Mol Life Sci. 2004. PMID: 15095009 Free PMC article. Review.

9

Ciglitazone inhibits plasmin-induced proinflammatory monocyte activation via modulation of p38 MAP kinase activity.

Syrovets T, Schüle A, Jendrach M, Büchele B, Simmet T. Syrovets T, et al. Among authors: simmet t. Thromb Haemost. 2002 Aug;88(2):274-81. Thromb Haemost. 2002. PMID: 12195700

10

Analysis of pentacyclic triterpenic acids from frankincense gum resins and related phytopharmaceuticals by high-performance liquid chromatography. Identification of lupeolic acid, a novel pentacyclic triterpene.

Büchele B, Zugmaier W, Simmet T. Büchele B, et al. Among authors: simmet t. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Jul 5;791(1-2):21-30. doi: 10.1016/s1570-0232(03)00160-0. J Chromatogr B Analyt Technol Biomed Life Sci. 2003. PMID: 12798161

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