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[Gly374Arg mutation in Fgfr3 causes achondroplasia in mice].
Wang JM, Du XL, Li CL, Yin LJ, Chen B, Sun J, Su N, Zhao L, Song RH, Song WW, Chen L, Deng CX. Wang JM, et al. Among authors: chen l, chen b. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2004 Dec;21(6):537-41. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2004. PMID: 15583977 Chinese.
Inducible Activation of FGFR2 in Adult Mice Promotes Bone Formation After Bone Marrow Ablation.
Xu W, Luo F, Wang Q, Tan Q, Huang J, Zhou S, Wang Z, Sun X, Kuang L, Jin M, Su N, Jiang W, Chen L, Qi H, Zhu Y, Chen B, Chen H, Chen S, Gao Y, Xu X, Deng C, Chen L, Xie Y, Du X. Xu W, et al. Among authors: chen l, chen b, chen s, chen h. J Bone Miner Res. 2017 Nov;32(11):2194-2206. doi: 10.1002/jbmr.3204. Epub 2017 Sep 12. J Bone Miner Res. 2017. PMID: 28650109 Free article.
FGFR3 deficient mice have accelerated fracture repair.
Xie Y, Luo F, Xu W, Wang Z, Sun X, Xu M, Huang J, Zhang D, Tan Q, Chen B, Jiang W, Du X, Chen L. Xie Y, et al. Among authors: chen l, chen b. Int J Biol Sci. 2017 Jul 18;13(8):1029-1037. doi: 10.7150/ijbs.19309. eCollection 2017. Int J Biol Sci. 2017. PMID: 28924384 Free PMC article.
PTH 1-34 Ameliorates the Osteopenia and Delayed Healing of Stabilized Tibia Fracture in Mice with Achondroplasia Resulting from Gain-Of-Function Mutation of FGFR3.
Chen H, Sun X, Yin L, Chen S, Zhu Y, Huang J, Jiang W, Chen B, Zhang R, Chen L, Nie M, Xie Y, Deng Z. Chen H, et al. Among authors: chen l, chen b, chen s. Int J Biol Sci. 2017 Sep 21;13(10):1254-1265. doi: 10.7150/ijbs.21258. eCollection 2017. Int J Biol Sci. 2017. PMID: 29104492 Free PMC article.
Rmrp Mutation Disrupts Chondrogenesis and Bone Ossification in Zebrafish Model of Cartilage-Hair Hypoplasia via Enhanced Wnt/β-Catenin Signaling.
Sun X, Zhang R, Liu M, Chen H, Chen L, Luo F, Zhang D, Huang J, Li F, Ni Z, Qi H, Su N, Jin M, Yang J, Tan Q, Du X, Chen B, Huang H, Chen S, Yin L, Xu X, Deng C, Luo L, Xie Y, Chen L. Sun X, et al. Among authors: chen l, chen b, chen s, chen h. J Bone Miner Res. 2019 Nov;34(11):2101-2116. doi: 10.1002/jbmr.3820. Epub 2019 Sep 4. J Bone Miner Res. 2019. PMID: 31237961 Free article.
Expansion of FGFR3-positive nucleus pulposus cells plays important roles in postnatal nucleus pulposus growth and regeneration.
Xu M, Huang J, Jin M, Jiang W, Luo F, Tan Q, Zhang R, Luo X, Kuang L, Zhang D, Liang S, Qi H, Chen H, Ni Z, Su N, Yang J, Du X, Chen B, Deng C, Xie Y, Chen L. Xu M, et al. Among authors: chen l, chen b, chen h. Stem Cell Res Ther. 2022 Jun 3;13(1):227. doi: 10.1186/s13287-022-02903-2. Stem Cell Res Ther. 2022. PMID: 35659742 Free PMC article.
Dstyk mutation leads to congenital scoliosis-like vertebral malformations in zebrafish via dysregulated mTORC1/TFEB pathway.
Sun X, Zhou Y, Zhang R, Wang Z, Xu M, Zhang D, Huang J, Luo F, Li F, Ni Z, Zhou S, Chen H, Chen S, Chen L, Du X, Chen B, Huang H, Liu P, Yin L, Qiu J, Chen D, Deng C, Xie Y, Luo L, Chen L. Sun X, et al. Among authors: chen l, chen b, chen s, chen d, chen h. Nat Commun. 2020 Jan 24;11(1):479. doi: 10.1038/s41467-019-14169-z. Nat Commun. 2020. PMID: 31980602 Free PMC article.
TGF-β/Alk5 signaling prevents osteoarthritis initiation via regulating the senescence of articular cartilage stem cells.
Tan Q, Wang Q, Kuang L, Zhang J, Peng X, Liang S, Liu M, Chen H, Chen S, Luo X, Qi H, Li C, Luo F, Huang S, Ni Z, Jin M, Su N, Yang J, Yang P, Chen B, Chen L, Du X, Xie Y, Chen L. Tan Q, et al. Among authors: chen l, chen b, chen s, chen h. J Cell Physiol. 2021 Jul;236(7):5278-5292. doi: 10.1002/jcp.30231. Epub 2021 Jan 16. J Cell Physiol. 2021. PMID: 33452687
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