Mutating a flexible region of the RSV F protein can stabilize the prefusion conformation.
Liang Y, Shao S, Li XY, Zhao ZX, Liu N, Liu ZM, Shen FJ, Zhang H, Hou JW, Zhang XF, Jin YQ, Du LF, Li X, Zhang J, Su JG, Li QM.
Liang Y, et al. Among authors: hou jw.
Science. 2024 Sep 27;385(6716):1484-1491. doi: 10.1126/science.adp2362. Epub 2024 Sep 26.
Science. 2024.
PMID: 39325881