Focher F - Search Results

1

Microwave-assisted synthesis and biological evaluation of novel uracil derivatives inhibiting human thymidine phosphorylase.

Corelli F, Botta M, Lossani A, Pasquini S, Spadari S, Focher F. Corelli F, et al. Among authors: focher f. Farmaco. 2004 Dec;59(12):987-92. doi: 10.1016/j.farmac.2004.08.007. Farmaco. 2004. PMID: 15598434

2

Simplified analogues of immucillin-G retain potent human purine nucleoside phosphorylase inhibitory activity.

Semeraro T, Lossani A, Botta M, Ghiron C, Alvarez R, Manetti F, Mugnaini C, Valensin S, Focher F, Corelli F. Semeraro T, et al. Among authors: focher f. J Med Chem. 2006 Oct 5;49(20):6037-45. doi: 10.1021/jm060547+. J Med Chem. 2006. PMID: 17004717

3

Research on L-nucleosides. Synthesis and biological evaluation of a series of L- and D-2',3'-dideoxy-3'-[tris(methylthio)methyl]-beta-pentofuranosyl nucleosides.

Mugnaini C, Botta M, Coletta M, Corelli F, Focher F, Marini S, Renzulli ML, Verri A. Mugnaini C, et al. Among authors: focher f. Bioorg Med Chem. 2003 Feb 6;11(3):357-66. doi: 10.1016/s0968-0896(02)00460-1. Bioorg Med Chem. 2003. PMID: 12517431

4

Synthesis and molecular modeling of novel HSV1 uracil-DNA glycosylase inhibitors.

Pregnolato M, Ubiali D, Verri A, Focher F, Spadari S, Sun H, Zhi C, Wright GE. Pregnolato M, et al. Among authors: focher f. Nucleosides Nucleotides. 1999 Apr-May;18(4-5):709-11. doi: 10.1080/15257779908041549. Nucleosides Nucleotides. 1999. PMID: 10432670

5

Novel nonsubstrate inhibitors of human thymidine phosphorylase, a potential target for tumor-dependent angiogenesis.

Focher F, Ubiali D, Pregnolato M, Zhi C, Gambino J, Wright GE, Spadari S. Focher F, et al. J Med Chem. 2000 Jun 29;43(13):2601-7. doi: 10.1021/jm000037u. J Med Chem. 2000. PMID: 10891120

6

Synthesis and in vitro activity of D- and L-enantiomers of 5-(trifluoromethyl)uracil nucleoside derivatives.

Salvetti R, Pregnolato M, Verri A, Focher F, Spadari S, Marchand A, Mathé C, Gosselin G. Salvetti R, et al. Among authors: focher f. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):1123-5. doi: 10.1081/NCN-100002502. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11562969

7

Thymidine phosphorylase: a two-face Janus in anticancer chemotherapy.

Focher F, Spadari S. Focher F, et al. Curr Cancer Drug Targets. 2001 Aug;1(2):141-53. doi: 10.2174/1568009013334232. Curr Cancer Drug Targets. 2001. PMID: 12188887 Review.

8

Herpes simplex virus type 1 uracil-DNA glycosylase: isolation and selective inhibition by novel uracil derivatives.

Focher F, Verri A, Spadari S, Manservigi R, Gambino J, Wright GE. Focher F, et al. Biochem J. 1993 Jun 15;292 ( Pt 3)(Pt 3):883-9. doi: 10.1042/bj2920883. Biochem J. 1993. PMID: 8391260 Free PMC article.

9

5-(Trifluoromethyl)-beta-l-2'-deoxyuridine, the L-enantiomer of trifluorothymidine: stereospecific synthesis and antiherpetic evaluations.

Salvetti R, Marchand A, Pregnolato M, Verri A, Spadari S, Focher F, Briant M, Sommadossi JP, Mathé C, Gosselin G. Salvetti R, et al. Among authors: focher f. Bioorg Med Chem. 2001 Jul;9(7):1731-8. doi: 10.1016/s0968-0896(01)00062-1. Bioorg Med Chem. 2001. PMID: 11425574

10

Inhibition of herpes simplex virus thymidine kinases by 2-phenylamino-6-oxopurines and related compounds: structure-activity relationships and antiherpetic activity in vivo.

Manikowski A, Verri A, Lossani A, Gebhardt BM, Gambino J, Focher F, Spadari S, Wright GE. Manikowski A, et al. Among authors: focher f. J Med Chem. 2005 Jun 2;48(11):3919-29. doi: 10.1021/jm049059x. J Med Chem. 2005. PMID: 15916444 Free PMC article.

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