Lossani A - Search Results

1

Microwave-assisted synthesis and biological evaluation of novel uracil derivatives inhibiting human thymidine phosphorylase.

Corelli F, Botta M, Lossani A, Pasquini S, Spadari S, Focher F. Corelli F, et al. Among authors: lossani a. Farmaco. 2004 Dec;59(12):987-92. doi: 10.1016/j.farmac.2004.08.007. Farmaco. 2004. PMID: 15598434

2

Simplified analogues of immucillin-G retain potent human purine nucleoside phosphorylase inhibitory activity.

Semeraro T, Lossani A, Botta M, Ghiron C, Alvarez R, Manetti F, Mugnaini C, Valensin S, Focher F, Corelli F. Semeraro T, et al. Among authors: lossani a. J Med Chem. 2006 Oct 5;49(20):6037-45. doi: 10.1021/jm060547+. J Med Chem. 2006. PMID: 17004717

3

Inhibition of herpes simplex virus thymidine kinases by 2-phenylamino-6-oxopurines and related compounds: structure-activity relationships and antiherpetic activity in vivo.

Manikowski A, Verri A, Lossani A, Gebhardt BM, Gambino J, Focher F, Spadari S, Wright GE. Manikowski A, et al. Among authors: lossani a. J Med Chem. 2005 Jun 2;48(11):3919-29. doi: 10.1021/jm049059x. J Med Chem. 2005. PMID: 15916444 Free PMC article.

4

Non-nucleoside inhibitors of human adenosine kinase: synthesis, molecular modeling, and biological studies.

Butini S, Gemma S, Brindisi M, Borrelli G, Lossani A, Ponte AM, Torti A, Maga G, Marinelli L, La Pietra V, Fiorini I, Lamponi S, Campiani G, Zisterer DM, Nathwani SM, Sartini S, La Motta C, Da Settimo F, Novellino E, Focher F. Butini S, et al. Among authors: lossani a. J Med Chem. 2011 Mar 10;54(5):1401-20. doi: 10.1021/jm101438u. Epub 2011 Feb 14. J Med Chem. 2011. PMID: 21319802

5

Thymidine kinase and uridine-cytidine kinase from Entamoeba histolytica: cloning, characterization, and search for specific inhibitors.

Lossani A, Torti A, Gatti S, Bruno A, Maserati R, Wright GE, Focher F. Lossani A, et al. Parasitology. 2009 May;136(6):595-602. doi: 10.1017/S0031182009005964. Epub 2009 Apr 16. Parasitology. 2009. PMID: 19368743

6

Enantioselectivity of ribonucleotide reductase: a first study using stereoisomers of pyrimidine 2'-azido-2'-deoxynucleosides.

Roy B, Verri A, Lossani A, Spadari S, Focher F, Aubertin AM, Gosselin G, Mathé C, Périgaud C. Roy B, et al. Among authors: lossani a. Biochem Pharmacol. 2004 Aug 15;68(4):711-8. doi: 10.1016/j.bcp.2004.05.002. Biochem Pharmacol. 2004. PMID: 15276078

7

Sensitivity of monkey B virus (Cercopithecine herpesvirus 1) to antiviral drugs: role of thymidine kinase in antiviral activities of substrate analogs and acyclonucleosides.

Focher F, Lossani A, Verri A, Spadari S, Maioli A, Gambino JJ, Wright GE, Eberle R, Black DH, Medveczky P, Medveczky M, Shugar D. Focher F, et al. Among authors: lossani a. Antimicrob Agents Chemother. 2007 Jun;51(6):2028-34. doi: 10.1128/AAC.01284-06. Epub 2007 Apr 16. Antimicrob Agents Chemother. 2007. PMID: 17438061 Free PMC article.

8

N²-Phenyl-9-(hydroxyalkyl)guanines and related compounds are substrates for Herpes simplex virus thymidine kinases.

Lossani A, Savi L, Manikowski A, Maioli A, Gambino J, Focher F, Spadari S, Wright GE. Lossani A, et al. J Mol Biochem. 2012;1(1):21-25. J Mol Biochem. 2012. PMID: 24734222 Free PMC article.

9

Site-directed Mutagenesis of Key Residues Unveiled a Novel Allosteric Site on Human Adenosine Kinase for Pyrrolobenzoxa(thia)zepinone Non-Nucleoside Inhibitors.

Savi L, Brindisi M, Alfano G, Butini S, La Pietra V, Novellino E, Marinelli L, Lossani A, Focher F, Cavella C, Campiani G, Gemma S. Savi L, et al. Among authors: lossani a. Chem Biol Drug Des. 2016 Jan;87(1):112-20. doi: 10.1111/cbdd.12630. Epub 2015 Sep 18. Chem Biol Drug Des. 2016. PMID: 26242695

10

Enantioselective binding of second generation pyrrolobenzoxazepinones to the catalytic ternary complex of HIV-1 RT wild-type and L100I and K103N drug resistant mutants.

Butini S, Gemma S, Brindisi M, Borrelli G, Fiorini I, Samuele A, Karytinos A, Facchini M, Lossani A, Zanoli S, Campiani G, Novellino E, Focher F, Maga G. Butini S, et al. Among authors: lossani a. Bioorg Med Chem Lett. 2011 Jul 1;21(13):3935-8. doi: 10.1016/j.bmcl.2011.05.020. Epub 2011 May 14. Bioorg Med Chem Lett. 2011. PMID: 21636271

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