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Page 1
The hypolipidemic natural product guggulsterone is a promiscuous steroid receptor ligand.
Burris TP, Montrose C, Houck KA, Osborne HE, Bocchinfuso WP, Yaden BC, Cheng CC, Zink RW, Barr RJ, Hepler CD, Krishnan V, Bullock HA, Burris LL, Galvin RJ, Bramlett K, Stayrook KR. Burris TP, et al. Among authors: hepler cd. Mol Pharmacol. 2005 Mar;67(3):948-54. doi: 10.1124/mol.104.007054. Epub 2004 Dec 15. Mol Pharmacol. 2005. PMID: 15602004
T0901317 is a dual LXR/FXR agonist.
Houck KA, Borchert KM, Hepler CD, Thomas JS, Bramlett KS, Michael LF, Burris TP. Houck KA, et al. Among authors: hepler cd. Mol Genet Metab. 2004 Sep-Oct;83(1-2):184-7. doi: 10.1016/j.ymgme.2004.07.007. Mol Genet Metab. 2004. PMID: 15464433
Structure-activity studies of 7-heteroaryl-3-azabicyclo[3.3.1]non-6-enes: a novel class of highly potent nicotinic receptor ligands.
Breining SR, Melvin M, Bhatti BS, Byrd GD, Kiser MN, Hepler CD, Hooker DN, Zhang J, Reynolds LA, Benson LR, Fedorov NB, Sidach SS, Mitchener JP, Lucero LM, Lukas RJ, Whiteaker P, Yohannes D. Breining SR, et al. Among authors: hepler cd. J Med Chem. 2012 Nov 26;55(22):9929-45. doi: 10.1021/jm3011299. Epub 2012 Oct 17. J Med Chem. 2012. PMID: 23025891
A dream deferred.
Hepler CD. Hepler CD. Am J Health Syst Pharm. 2010 Aug 15;67(16):1319-25. doi: 10.2146/ajhp100329. Am J Health Syst Pharm. 2010. PMID: 20689120 No abstract available.
78 results