Melchor JP - Search Results

1

Ethanol-withdrawal seizures are controlled by tissue plasminogen activator via modulation of NR2B-containing NMDA receptors.

Pawlak R, Melchor JP, Matys T, Skrzypiec AE, Strickland S. Pawlak R, et al. Among authors: melchor jp. Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):443-8. doi: 10.1073/pnas.0406454102. Epub 2005 Jan 3. Proc Natl Acad Sci U S A. 2005. PMID: 15630096 Free PMC article.

2

The possible role of tissue-type plasminogen activator (tPA) and tPA blockers in the pathogenesis and treatment of Alzheimer's disease.

Melchor JP, Pawlak R, Chen Z, Strickland S. Melchor JP, et al. J Mol Neurosci. 2003;20(3):287-9. doi: 10.1385/JMN:20:3:287. J Mol Neurosci. 2003. PMID: 14501010

3

The tissue plasminogen activator-plasminogen proteolytic cascade accelerates amyloid-beta (Abeta) degradation and inhibits Abeta-induced neurodegeneration.

Melchor JP, Pawlak R, Strickland S. Melchor JP, et al. J Neurosci. 2003 Oct 1;23(26):8867-71. doi: 10.1523/JNEUROSCI.23-26-08867.2003. J Neurosci. 2003. PMID: 14523088 Free PMC article.

4

Tissue plasminogen activator in central nervous system physiology and pathology.

Melchor JP, Strickland S. Melchor JP, et al. Thromb Haemost. 2005 Apr;93(4):655-60. doi: 10.1160/TH04-12-0838. Thromb Haemost. 2005. PMID: 15841309 Free PMC article. Review.

5

Tissue plasminogen activator and plasminogen mediate stress-induced decline of neuronal and cognitive functions in the mouse hippocampus.

Pawlak R, Rao BS, Melchor JP, Chattarji S, McEwen B, Strickland S. Pawlak R, et al. Among authors: melchor jp. Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):18201-6. doi: 10.1073/pnas.0509232102. Epub 2005 Dec 5. Proc Natl Acad Sci U S A. 2005. PMID: 16330749 Free PMC article.

6

Tissue plasminogen activator in the amygdala is critical for stress-induced anxiety-like behavior.

Pawlak R, Magarinos AM, Melchor J, McEwen B, Strickland S. Pawlak R, et al. Nat Neurosci. 2003 Feb;6(2):168-74. doi: 10.1038/nn998. Nat Neurosci. 2003. PMID: 12524546

7

Modulation of sympathetic activity by tissue plasminogen activator is independent of plasminogen and urokinase.

Schaefer U, Vorlova S, Machida T, Melchor JP, Strickland S, Levi R. Schaefer U, et al. Among authors: melchor jp. J Pharmacol Exp Ther. 2007 Jul;322(1):265-73. doi: 10.1124/jpet.107.121335. Epub 2007 Apr 11. J Pharmacol Exp Ther. 2007. PMID: 17429057 Free article.

8

Fibrin deposition accelerates neurovascular damage and neuroinflammation in mouse models of Alzheimer's disease.

Paul J, Strickland S, Melchor JP. Paul J, et al. Among authors: melchor jp. J Exp Med. 2007 Aug 6;204(8):1999-2008. doi: 10.1084/jem.20070304. Epub 2007 Jul 30. J Exp Med. 2007. PMID: 17664291 Free PMC article.

9

Unbiased in vivo preclinical evaluation of anticancer drugs identifies effective therapy for the treatment of pancreatic adenocarcinoma.

Grbovic-Huezo O, Pitter KL, Lecomte N, Saglimbeni J, Askan G, Holm M, Melchor JP, Chandwani R, Joshi S, Haglund C, Iacobuzio-Donahue CA, Chiosis G, Tammela T, Leach SD. Grbovic-Huezo O, et al. Among authors: melchor jp. Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30670-30678. doi: 10.1073/pnas.1920240117. Epub 2020 Nov 16. Proc Natl Acad Sci U S A. 2020. PMID: 33199632 Free PMC article.

10

Pancreatic cancer prognosis is predicted by an ATAC-array technology for assessing chromatin accessibility.

Dhara S, Chhangawala S, Chintalapudi H, Askan G, Aveson V, Massa AL, Zhang L, Torres D, Makohon-Moore AP, Lecomte N, Melchor JP, Bermeo J, Cardenas A 3rd, Sinha S, Glassman D, Nicolle R, Moffitt R, Yu KH, Leppanen S, Laderman S, Curry B, Gui J, Balachandran VP, Iacobuzio-Donahue C, Chandwani R, Leslie CS, Leach SD. Dhara S, et al. Among authors: melchor jp. Nat Commun. 2021 May 24;12(1):3044. doi: 10.1038/s41467-021-23237-2. Nat Commun. 2021. PMID: 34031415 Free PMC article.

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