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Depsipeptide (FR 901228) promotes histone acetylation, gene transcription, apoptosis and its activity is enhanced by DNA methyltransferase inhibitors in AML1/ETO-positive leukemic cells.
Klisovic MI, Maghraby EA, Parthun MR, Guimond M, Sklenar AR, Whitman SP, Chan KK, Murphy T, Anon J, Archer KJ, Rush LJ, Plass C, Grever MR, Byrd JC, Marcucci G. Klisovic MI, et al. Among authors: byrd jc. Leukemia. 2003 Feb;17(2):350-8. doi: 10.1038/sj.leu.2402776. Leukemia. 2003. PMID: 12592335
Core binding factor acute myeloid leukemia. Cancer and Leukemia Group B (CALGB) Study 8461.
Bloomfield CD, Ruppert AS, Mrózek K, Kolitz JE, Moore JO, Mayer RJ, Edwards CG, Sterling LJ, Vardiman JW, Carroll AJ, Pettenati MJ, Stamberg J, Byrd JC, Marcucci G, Larson RA; Cancer and Leukemia Group B (CALGB) Study 8461. Bloomfield CD, et al. Among authors: byrd jc. Ann Hematol. 2004;83 Suppl 1:S84-5. doi: 10.1007/s00277-004-0850-2. Ann Hematol. 2004. PMID: 15124687 No abstract available.
G3139, a BCL-2 antisense oligo-nucleotide, in AML.
Marcucci G, Stock W, Dai G, Klisovic MI, Maharry K, Shen T, Liu S, Sher DA, Lucas D, Zwiebel A, Larson RA, Caligiuri MA, Bloomfield CD, Chan KK, Grever MR, Byrd JC. Marcucci G, et al. Among authors: byrd jc. Ann Hematol. 2004;83 Suppl 1:S93-4. doi: 10.1007/s00277-004-0850-2. Ann Hematol. 2004. PMID: 15124691 Clinical Trial. No abstract available.
High-dose busulfan, cyclophosphamide, and etoposide does not improve outcome of allogeneic stem cell transplantation compared to BuCy2 in patients with acute myeloid leukemia.
Farag SS, Bolwell BJ, Elder PJ, Kalaycio M, Lin T, Pohlman B, Penza S, Marcucci G, Blum W, Sobecks R, Avalos BR, Byrd JC, Copelan E. Farag SS, et al. Among authors: byrd jc. Bone Marrow Transplant. 2005 Apr;35(7):653-61. doi: 10.1038/sj.bmt.1704867. Bone Marrow Transplant. 2005. PMID: 15711571 Clinical Trial.
Chemoresistance to depsipeptide FK228 [(E)-(1S,4S,10S,21R)-7-[(Z)-ethylidene]-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8,7,6]-tricos-16-ene-3,6,9,22-pentanone] is mediated by reversible MDR1 induction in human cancer cell lines.
Xiao JJ, Huang Y, Dai Z, Sadée W, Chen J, Liu S, Marcucci G, Byrd J, Covey JM, Wright J, Grever M, Chan KK. Xiao JJ, et al. Among authors: byrd j. J Pharmacol Exp Ther. 2005 Jul;314(1):467-75. doi: 10.1124/jpet.105.083956. Epub 2005 Apr 15. J Pharmacol Exp Ther. 2005. PMID: 15833893
1,569 results