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Page 1
Stat5 tetramer formation is associated with leukemogenesis.
Moriggl R, Sexl V, Kenner L, Duntsch C, Stangl K, Gingras S, Hoffmeyer A, Bauer A, Piekorz R, Wang D, Bunting KD, Wagner EF, Sonneck K, Valent P, Ihle JN, Beug H. Moriggl R, et al. Among authors: beug h. Cancer Cell. 2005 Jan;7(1):87-99. doi: 10.1016/j.ccr.2004.12.010. Cancer Cell. 2005. PMID: 15652752 Free article.
STAT1 acts as a tumor promoter for leukemia development.
Kovacic B, Stoiber D, Moriggl R, Weisz E, Ott RG, Kreibich R, Levy DE, Beug H, Freissmuth M, Sexl V. Kovacic B, et al. Among authors: beug h. Cancer Cell. 2006 Jul;10(1):77-87. doi: 10.1016/j.ccr.2006.05.025. Cancer Cell. 2006. PMID: 16843267 Free article.
The different functions of Stat5 and chromatin alteration through Stat5 proteins.
Kornfeld JW, Grebien F, Kerenyi MA, Friedbichler K, Kovacic B, Zankl B, Hoelbl A, Nivarti H, Beug H, Sexl V, Muller M, Kenner L, Mullner EW, Gouilleux F, Moriggl R. Kornfeld JW, et al. Among authors: beug h. Front Biosci. 2008 May 1;13:6237-54. doi: 10.2741/3151. Front Biosci. 2008. PMID: 18508657 Free PMC article. Review.
Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation.
Friedbichler K, Kerenyi MA, Kovacic B, Li G, Hoelbl A, Yahiaoui S, Sexl V, Müllner EW, Fajmann S, Cerny-Reiterer S, Valent P, Beug H, Gouilleux F, Bunting KD, Moriggl R. Friedbichler K, et al. Among authors: beug h. Blood. 2010 Sep 2;116(9):1548-58. doi: 10.1182/blood-2009-12-258913. Epub 2010 May 27. Blood. 2010. PMID: 20508164 Free PMC article.
Stat5 is indispensable for the maintenance of bcr/abl-positive leukaemia.
Hoelbl A, Schuster C, Kovacic B, Zhu B, Wickre M, Hoelzl MA, Fajmann S, Grebien F, Warsch W, Stengl G, Hennighausen L, Poli V, Beug H, Moriggl R, Sexl V. Hoelbl A, et al. Among authors: beug h. EMBO Mol Med. 2010 Mar;2(3):98-110. doi: 10.1002/emmm.201000062. EMBO Mol Med. 2010. PMID: 20201032 Free PMC article.
Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis.
Grebien F, Hantschel O, Wojcik J, Kaupe I, Kovacic B, Wyrzucki AM, Gish GD, Cerny-Reiterer S, Koide A, Beug H, Pawson T, Valent P, Koide S, Superti-Furga G. Grebien F, et al. Among authors: beug h. Cell. 2011 Oct 14;147(2):306-19. doi: 10.1016/j.cell.2011.08.046. Cell. 2011. PMID: 22000011 Free PMC article.
279 results