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Methylation of the imidazole side chains of the Alzheimer disease amyloid-beta peptide results in abolition of superoxide dismutase-like structures and inhibition of neurotoxicity.
Tickler AK, Smith DG, Ciccotosto GD, Tew DJ, Curtain CC, Carrington D, Masters CL, Bush AI, Cherny RA, Cappai R, Wade JD, Barnham KJ. Tickler AK, et al. J Biol Chem. 2005 Apr 8;280(14):13355-63. doi: 10.1074/jbc.M414178200. Epub 2005 Jan 24. J Biol Chem. 2005. PMID: 15668252 Free article.
Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation.
Barnham KJ, Ciccotosto GD, Tickler AK, Ali FE, Smith DG, Williamson NA, Lam YH, Carrington D, Tew D, Kocak G, Volitakis I, Separovic F, Barrow CJ, Wade JD, Masters CL, Cherny RA, Curtain CC, Bush AI, Cappai R. Barnham KJ, et al. Among authors: tickler ak. J Biol Chem. 2003 Oct 31;278(44):42959-65. doi: 10.1074/jbc.M305494200. Epub 2003 Aug 18. J Biol Chem. 2003. PMID: 12925530 Free article.
The role of Abeta peptides in Alzheimer's disease.
Tickler AK, Wade JD, Separovic F. Tickler AK, et al. Protein Pept Lett. 2005 Aug;12(6):513-9. doi: 10.2174/0929866054395905. Protein Pept Lett. 2005. PMID: 16101387 Review.
Functionalised amyloid fibrils for roles in cell adhesion.
Gras SL, Tickler AK, Squires AM, Devlin GL, Horton MA, Dobson CM, MacPhee CE. Gras SL, et al. Among authors: tickler ak. Biomaterials. 2008 Apr;29(11):1553-62. doi: 10.1016/j.biomaterials.2007.11.028. Epub 2007 Dec 31. Biomaterials. 2008. PMID: 18164758
11 results