Gibbs JB - Search Results

1

Steady-state kinetic mechanism of Ras farnesyl:protein transferase.

Pompliano DL, Rands E, Schaber MD, Mosser SD, Anthony NJ, Gibbs JB. Pompliano DL, et al. Among authors: gibbs jb. Biochemistry. 1992 Apr 21;31(15):3800-7. doi: 10.1021/bi00130a010. Biochemistry. 1992. PMID: 1567835

2

Polyisoprenylation of Ras in vitro by a farnesyl-protein transferase.

Schaber MD, O'Hara MB, Garsky VM, Mosser SC, Bergstrom JD, Moores SL, Marshall MS, Friedman PA, Dixon RA, Gibbs JB. Schaber MD, et al. Among authors: gibbs jb. J Biol Chem. 1990 Sep 5;265(25):14701-4. J Biol Chem. 1990. PMID: 2203759 Free article.

3

Synthesis and biological activity of ras farnesyl protein transferase inhibitors. Tetrapeptide analogs with amino methyl and carbon linkages.

Wai JS, Bamberger DL, Fisher TE, Graham SL, Smith RL, Gibbs JB, Mosser SD, Oliff AI, Pompliano DL, Rands E, et al. Wai JS, et al. Among authors: gibbs jb. Bioorg Med Chem. 1994 Sep;2(9):939-47. doi: 10.1016/s0968-0896(00)82043-x. Bioorg Med Chem. 1994. PMID: 7712129

4

Selective inhibition of ras-dependent transformation by a farnesyltransferase inhibitor.

Kohl NE, Mosser SD, deSolms SJ, Giuliani EA, Pompliano DL, Graham SL, Smith RL, Scolnick EM, Oliff A, Gibbs JB. Kohl NE, et al. Among authors: gibbs jb. Science. 1993 Jun 25;260(5116):1934-7. doi: 10.1126/science.8316833. Science. 1993. PMID: 8316833

5

Isoprenoid diphosphate utilization by recombinant human farnesyl:protein transferase: interactive binding between substrates and a preferred kinetic pathway.

Pompliano DL, Schaber MD, Mosser SD, Omer CA, Shafer JA, Gibbs JB. Pompliano DL, et al. Among authors: gibbs jb. Biochemistry. 1993 Aug 17;32(32):8341-7. doi: 10.1021/bi00083a038. Biochemistry. 1993. PMID: 8347630

6

Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo.

Gibbs JB, Pompliano DL, Mosser SD, Rands E, Lingham RB, Singh SB, Scolnick EM, Kohl NE, Oliff A. Gibbs JB, et al. J Biol Chem. 1993 Apr 15;268(11):7617-20. J Biol Chem. 1993. PMID: 8463291 Free article.

7

Inhibition of Ras function in vitro and in vivo using inhibitors of farnesyl-protein transferase.

Kohl NE, Wilson FR, Thomas TJ, Bock RL, Mosser SD, Oliff A, Gibbs JB. Kohl NE, et al. Among authors: gibbs jb. Methods Enzymol. 1995;255:378-86. doi: 10.1016/s0076-6879(95)55040-2. Methods Enzymol. 1995. PMID: 8524123 No abstract available.

8

Design and in vivo analysis of potent non-thiol inhibitors of farnesyl protein transferase.

Anthony NJ, Gomez RP, Schaber MD, Mosser SD, Hamilton KA, O'Neil TJ, Koblan KS, Graham SL, Hartman GD, Shah D, Rands E, Kohl NE, Gibbs JB, Oliff AI. Anthony NJ, et al. Among authors: gibbs jb. J Med Chem. 1999 Aug 26;42(17):3356-68. doi: 10.1021/jm990080l. J Med Chem. 1999. PMID: 10464022

9

Mouse mammary tumor virus-Ki-rasB transgenic mice develop mammary carcinomas that can be growth-inhibited by a farnesyl:protein transferase inhibitor.

Omer CA, Chen Z, Diehl RE, Conner MW, Chen HY, Trumbauer ME, Gopal-Truter S, Seeburger G, Bhimnathwala H, Abrams MT, Davide JP, Ellis MS, Gibbs JB, Greenberg I, Koblan KS, Kral AM, Liu D, Lobell RB, Miller PJ, Mosser SD, O'Neill TJ, Rands E, Schaber MD, Senderak ET, Oliff A, Kohl NE. Omer CA, et al. Among authors: gibbs jb. Cancer Res. 2000 May 15;60(10):2680-8. Cancer Res. 2000. PMID: 10825141

10

Sequence dependence of protein isoprenylation.

Moores SL, Schaber MD, Mosser SD, Rands E, O'Hara MB, Garsky VM, Marshall MS, Pompliano DL, Gibbs JB. Moores SL, et al. Among authors: gibbs jb. J Biol Chem. 1991 Aug 5;266(22):14603-10. J Biol Chem. 1991. PMID: 1860864 Free article.

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