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Heterocyclic and phenyl double-bond-locked combretastatin analogues possessing potent apoptosis-inducing activity in HL60 and in MDR cell lines.
Simoni D, Grisolia G, Giannini G, Roberti M, Rondanin R, Piccagli L, Baruchello R, Rossi M, Romagnoli R, Invidiata FP, Grimaudo S, Jung MK, Hamel E, Gebbia N, Crosta L, Abbadessa V, Di Cristina A, Dusonchet L, Meli M, Tolomeo M. Simoni D, et al. Among authors: rossi m. J Med Chem. 2005 Feb 10;48(3):723-36. doi: 10.1021/jm049622b. J Med Chem. 2005. PMID: 15689156
Synthesis and pharmacology of 6-substituted benztropines: discovery of novel dopamine uptake inhibitors possessing low binding affinity to the dopamine transporter.
Simoni D, Rossi M, Bertolasi V, Roberti M, Pizzirani D, Rondanin R, Baruchello R, Invidiata FP, Tolomeo M, Grimaudo S, Merighi S, Varani K, Gessi S, Borea PA, Marino S, Cavallini S, Bianchi C, Siniscalchi A. Simoni D, et al. Among authors: rossi m. J Med Chem. 2005 May 5;48(9):3337-43. doi: 10.1021/jm0490235. J Med Chem. 2005. PMID: 15857139
Studies on the apoptotic activity of natural and synthetic retinoids: discovery of a new class of synthetic terphenyls that potently support cell growth and inhibit apoptosis in neuronal and HL-60 cells.
Simoni D, Giannini G, Roberti M, Rondanin R, Baruchello R, Rossi M, Grisolia G, Invidiata FP, Aiello S, Marino S, Cavallini S, Siniscalchi A, Gebbia N, Crosta L, Grimaudo S, Abbadessa V, Di Cristina A, Tolomeo M. Simoni D, et al. Among authors: rossi m. J Med Chem. 2005 Jun 30;48(13):4293-9. doi: 10.1021/jm049080y. J Med Chem. 2005. PMID: 15974583
Programmed cell death (PCD) associated with the stilbene motif of arotinoids: discovery of novel apoptosis inducer agents possessing activity on multidrug resistant tumor cells.
Simoni D, Roberti M, Invidiata FP, Rondanin R, Baruchello R, Malagutti C, Mazzali A, Rossi M, Grimaudo S, Dusonchet L, Meli M, Raimondi MV, D'Alessandro N, Tolomeo M. Simoni D, et al. Among authors: rossi m. Bioorg Med Chem Lett. 2000 Dec 4;10(23):2669-73. doi: 10.1016/s0960-894x(00)00547-3. Bioorg Med Chem Lett. 2000. PMID: 11128648
Heterocycle-containing retinoids. Discovery of a novel isoxazole arotinoid possessing potent apoptotic activity in multidrug and drug-induced apoptosis-resistant cells.
Simoni D, Roberti M, Invidiata FP, Rondanin R, Baruchello R, Malagutti C, Mazzali A, Rossi M, Grimaudo S, Capone F, Dusonchet L, Meli M, Raimondi MV, Landino M, D'Alessandro N, Tolomeo M, Arindam D, Lu S, Benbrook DM. Simoni D, et al. Among authors: rossi m. J Med Chem. 2001 Jul 5;44(14):2308-18. doi: 10.1021/jm0010320. J Med Chem. 2001. PMID: 11428925
6,456 results