Cabot M - Search Results

1

Potentiation of cell killing by fractionated radiation and suppression of proliferative recovery in MCF-7 breast tumor cells by the Vitamin D3 analog EB 1089.

DeMasters GA, Gupta MS, Jones KR, Cabot M, Wang H, Gennings C, Park M, Bratland A, Ree AH, Gewirtz DA. DeMasters GA, et al. Among authors: cabot m. J Steroid Biochem Mol Biol. 2004 Dec;92(5):365-74. doi: 10.1016/j.jsbmb.2004.07.011. Epub 2004 Dec 21. J Steroid Biochem Mol Biol. 2004. PMID: 15698541

2

Autophagic cell death, polyploidy and senescence induced in breast tumor cells by the substituted pyrrole JG-03-14, a novel microtubule poison.

Arthur CR, Gupton JT, Kellogg GE, Yeudall WA, Cabot MC, Newsham IF, Gewirtz DA. Arthur CR, et al. Biochem Pharmacol. 2007 Oct 1;74(7):981-91. doi: 10.1016/j.bcp.2007.07.003. Epub 2007 Jul 7. Biochem Pharmacol. 2007. PMID: 17692290 Free PMC article.

3

Enhanced de novo ceramide generation through activation of serine palmitoyltransferase by the P-glycoprotein antagonist SDZ PSC 833 in breast cancer cells.

Wang H, Giuliano AE, Cabot MC. Wang H, et al. Mol Cancer Ther. 2002 Jul;1(9):719-26. Mol Cancer Ther. 2002. PMID: 12479368

4

Increasing intracellular ceramide: an approach that enhances the cytotoxic response in prostate cancer cells.

Wang H, Charles AG, Frankel AJ, Cabot MC. Wang H, et al. Urology. 2003 May;61(5):1047-52. doi: 10.1016/s0090-4295(02)02511-6. Urology. 2003. PMID: 12736045

5

N-(4-hydroxyphenyl)retinamide elevates ceramide in neuroblastoma cell lines by coordinate activation of serine palmitoyltransferase and ceramide synthase.

Wang H, Maurer BJ, Reynolds CP, Cabot MC. Wang H, et al. Among authors: cabot mc. Cancer Res. 2001 Jul 1;61(13):5102-5. Cancer Res. 2001. PMID: 11431347

6

N-(4-Hydroxyphenyl)retinamide increases dihydroceramide and synergizes with dimethylsphingosine to enhance cancer cell killing.

Wang H, Maurer BJ, Liu YY, Wang E, Allegood JC, Kelly S, Symolon H, Liu Y, Merrill AH Jr, Gouazé-Andersson V, Yu JY, Giuliano AE, Cabot MC. Wang H, et al. Mol Cancer Ther. 2008 Sep;7(9):2967-76. doi: 10.1158/1535-7163.MCT-08-0549. Mol Cancer Ther. 2008. PMID: 18790777

7

Overexpression of glucosylceramide synthase and P-glycoprotein in cancer cells selected for resistance to natural product chemotherapy.

Gouazé V, Yu JY, Bleicher RJ, Han TY, Liu YY, Wang H, Gottesman MM, Bitterman A, Giuliano AE, Cabot MC. Gouazé V, et al. Among authors: cabot mc. Mol Cancer Ther. 2004 May;3(5):633-9. Mol Cancer Ther. 2004. PMID: 15141021

8

Chemotherapy selection pressure alters sphingolipid composition and mitochondrial bioenergetics in resistant HL-60 cells.

Kao LP, Morad SAF, Davis TS, MacDougall MR, Kassai M, Abdelmageed N, Fox TE, Kester M, Loughran TP Jr, Abad JL, Fabrias G, Tan SF, Feith DJ, Claxton DF, Spiegel S, Fisher-Wellman KH, Cabot MC. Kao LP, et al. Among authors: cabot mc. J Lipid Res. 2019 Sep;60(9):1590-1602. doi: 10.1194/jlr.RA119000251. Epub 2019 Jul 30. J Lipid Res. 2019. PMID: 31363040 Free PMC article.

9

Enhanced ceramide generation and induction of apoptosis in human leukemia cells exposed to DT(388)-granulocyte-macrophage colony-stimulating factor (GM-CSF), a truncated diphtheria toxin fused to human GM-CSF.

Senchenkov A, Han TY, Wang H, Frankel AE, Kottke TJ, Kaufmann SH, Cabot MC. Senchenkov A, et al. Among authors: cabot mc. Blood. 2001 Sep 15;98(6):1927-34. doi: 10.1182/blood.v98.6.1927. Blood. 2001. PMID: 11535531 Free article.

10

Acid ceramidase is upregulated in AML and represents a novel therapeutic target.

Tan SF, Liu X, Fox TE, Barth BM, Sharma A, Turner SD, Awwad A, Dewey A, Doi K, Spitzer B, Shah MV, Morad SA, Desai D, Amin S, Zhu J, Liao J, Yun J, Kester M, Claxton DF, Wang HG, Cabot MC, Schuchman EH, Levine RL, Feith DJ, Loughran TP Jr. Tan SF, et al. Among authors: cabot mc. Oncotarget. 2016 Dec 13;7(50):83208-83222. doi: 10.18632/oncotarget.13079. Oncotarget. 2016. PMID: 27825124 Free PMC article.

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