Schaer D - Search Results

1

Defective proximal TCR signaling inhibits CD8+ tumor-infiltrating lymphocyte lytic function.

Koneru M, Schaer D, Monu N, Ayala A, Frey AB. Koneru M, et al. Among authors: schaer d. J Immunol. 2005 Feb 15;174(4):1830-40. doi: 10.4049/jimmunol.174.4.1830. J Immunol. 2005. PMID: 15699109

2

Defective adhesion in tumor infiltrating CD8+ T cells.

Koneru M, Monu N, Schaer D, Barletta J, Frey AB. Koneru M, et al. Among authors: schaer d. J Immunol. 2006 May 15;176(10):6103-11. doi: 10.4049/jimmunol.176.10.6103. J Immunol. 2006. PMID: 16670319

3

CD8(+) tumor-infiltrating T cells are deficient in perforin-mediated cytolytic activity due to defective microtubule-organizing center mobilization and lytic granule exocytosis.

Radoja S, Saio M, Schaer D, Koneru M, Vukmanovic S, Frey AB. Radoja S, et al. Among authors: schaer d. J Immunol. 2001 Nov 1;167(9):5042-51. doi: 10.4049/jimmunol.167.9.5042. J Immunol. 2001. PMID: 11673513

4

Calcitonin gene-related peptide decreases expression of HLA-DR and CD86 by human dendritic cells and dampens dendritic cell-driven T cell-proliferative responses via the type I calcitonin gene-related peptide receptor.

Carucci JA, Ignatius R, Wei Y, Cypess AM, Schaer DA, Pope M, Steinman RM, Mojsov S. Carucci JA, et al. Among authors: schaer da. J Immunol. 2000 Apr 1;164(7):3494-9. doi: 10.4049/jimmunol.164.7.3494. J Immunol. 2000. PMID: 10725702

5

GITR pathway activation abrogates tumor immune suppression through loss of regulatory T cell lineage stability.

Schaer DA, Budhu S, Liu C, Bryson C, Malandro N, Cohen A, Zhong H, Yang X, Houghton AN, Merghoub T, Wolchok JD. Schaer DA, et al. Cancer Immunol Res. 2013 Nov;1(5):320-31. doi: 10.1158/2326-6066.CIR-13-0086. Cancer Immunol Res. 2013. PMID: 24416730 Free PMC article.

6

Anti-GITR antibodies--potential clinical applications for tumor immunotherapy.

Schaer DA, Cohen AD, Wolchok JD. Schaer DA, et al. Curr Opin Investig Drugs. 2010 Dec;11(12):1378-86. Curr Opin Investig Drugs. 2010. PMID: 21154120 Review.

7

Blockade of surface-bound TGF-β on regulatory T cells abrogates suppression of effector T cell function in the tumor microenvironment.

Budhu S, Schaer DA, Li Y, Toledo-Crow R, Panageas K, Yang X, Zhong H, Houghton AN, Silverstein SC, Merghoub T, Wolchok JD. Budhu S, et al. Among authors: schaer da. Sci Signal. 2017 Aug 29;10(494):eaak9702. doi: 10.1126/scisignal.aak9702. Sci Signal. 2017. PMID: 28851824 Free PMC article.

8

Agonist anti-GITR monoclonal antibody induces melanoma tumor immunity in mice by altering regulatory T cell stability and intra-tumor accumulation.

Cohen AD, Schaer DA, Liu C, Li Y, Hirschhorn-Cymmerman D, Kim SC, Diab A, Rizzuto G, Duan F, Perales MA, Merghoub T, Houghton AN, Wolchok JD. Cohen AD, et al. Among authors: schaer da. PLoS One. 2010 May 3;5(5):e10436. doi: 10.1371/journal.pone.0010436. PLoS One. 2010. PMID: 20454651 Free PMC article.

9

Detection of intra-tumor self antigen recognition during melanoma tumor progression in mice using advanced multimode confocal/two photon microscope.

Schaer DA, Li Y, Merghoub T, Rizzuto GA, Shemesh A, Cohen AD, Li Y, Avogadri F, Toledo-Crow R, Houghton AN, Wolchok JD. Schaer DA, et al. PLoS One. 2011;6(6):e21214. doi: 10.1371/journal.pone.0021214. Epub 2011 Jun 22. PLoS One. 2011. PMID: 21731676 Free PMC article.

10

Hiding the road signs that lead to tumor immunity.

Schaer DA, Lesokhin AM, Wolchok JD. Schaer DA, et al. J Exp Med. 2011 Sep 26;208(10):1937-40. doi: 10.1084/jem.20111856. J Exp Med. 2011. PMID: 21948803 Free PMC article. Review.

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