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Page 1
CoMFA, synthesis, and pharmacological evaluation of (E)-3-(2-carboxy-2-arylvinyl)-4,6-dichloro-1H-indole-2-carboxylic acids: 3-[2-(3-aminophenyl)-2-carboxyvinyl]-4,6-dichloro-1H-indole-2-carboxylic acid, a potent selective glycine-site NMDA receptor antagonist.
Baron BM, Cregge RJ, Farr RA, Friedrich D, Gross RS, Harrison BL, Janowick DA, Matthews D, McCloskey TC, Meikrantz S, Nyce PL, Vaz R, Metz WA. Baron BM, et al. Among authors: friedrich d. J Med Chem. 2005 Feb 24;48(4):995-1018. doi: 10.1021/jm0491849. J Med Chem. 2005. PMID: 15715469
Novel steroidal vinyl fluorides as inhibitors of steroid C17(20) lyase.
Burkhart JP, Weintraub PM, Gates CA, Resvick RJ, Vaz RJ, Friedrich D, Angelastro MR, Bey P, Peet NP. Burkhart JP, et al. Among authors: friedrich d. Bioorg Med Chem. 2002 Apr;10(4):929-34. doi: 10.1016/s0968-0896(01)00354-6. Bioorg Med Chem. 2002. PMID: 11836100
Cyclic nitrone free radical traps: isolation, identification, and synthesis of 3,3-dimethyl-3,4-dihydroisoquinolin-4-ol N-oxide, a metabolite with reduced side effects.
Thomas CE, Bernardelli P, Bowen SM, Chaney SF, Friedrich D, Janowick DA, Jones BK, Keeley FJ, Kehne JH, Ketteler B, Ohlweiler DF, Paquette LA, Robke DJ, Fevig TL. Thomas CE, et al. Among authors: friedrich d. J Med Chem. 1996 Dec 6;39(25):4997-5004. doi: 10.1021/jm960244n. J Med Chem. 1996. PMID: 8960560
Hydroxyoxazolidines as alpha-aminoacetaldehye equivalents: novel inhibitors of calpain.
Peet NP, Kim HO, Marquart AL, Angelastro MR, Nieduzak TR, White JN, Friedrich D, Flynn GA, Webster ME, Vaz RJ, Linnik MD, Koehl JR, Mehdi S, Bey P, Emary B, Hwang KK. Peet NP, et al. Among authors: friedrich d. Bioorg Med Chem Lett. 1999 Aug 16;9(16):2365-70. doi: 10.1016/s0960-894x(99)00391-1. Bioorg Med Chem Lett. 1999. PMID: 10476870
Revised constitution of sclerophytins A and B.
Friedrich D, Doskotch RW, Paquette LA. Friedrich D, et al. Org Lett. 2000 Jun 29;2(13):1879-82. doi: 10.1021/ol000084g. Org Lett. 2000. PMID: 10891181
252 results