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An apolipoprotein B antisense oligonucleotide lowers LDL cholesterol in hyperlipidemic mice without causing hepatic steatosis.
J Lipid Res. 2005 May;46(5):872-84. doi: 10.1194/jlr.M400492-JLR200. Epub 2005 Feb 16.
J Lipid Res. 2005.
PMID: 15716585
Free article.
Antisense inhibition of proprotein convertase subtilisin/kexin type 9 reduces serum LDL in hyperlipidemic mice.
Graham MJ, Lemonidis KM, Whipple CP, Subramaniam A, Monia BP, Crooke ST, Crooke RM.
Graham MJ, et al. Among authors: whipple cp.
J Lipid Res. 2007 Apr;48(4):763-7. doi: 10.1194/jlr.C600025-JLR200. Epub 2007 Jan 22.
J Lipid Res. 2007.
PMID: 17242417
Free article.
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Antisense oligonucleotide reduction of apoB-ameliorated atherosclerosis in LDL receptor-deficient mice.
Mullick AE, Fu W, Graham MJ, Lee RG, Witchell D, Bell TA, Whipple CP, Crooke RM.
Mullick AE, et al. Among authors: whipple cp.
J Lipid Res. 2011 May;52(5):885-96. doi: 10.1194/jlr.M011791. Epub 2011 Feb 22.
J Lipid Res. 2011.
PMID: 21343632
Free PMC article.
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