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Asparagine synthetase expression is linked with L-asparaginase resistance in TEL-AML1-negative but not TEL-AML1-positive pediatric acute lymphoblastic leukemia.

Stams WA, den Boer ML, Holleman A, Appel IM, Beverloo HB, van Wering ER, Janka-Schaub GE, Evans WE, Pieters R. Stams WA, et al. Blood. 2005 Jun 1;105(11):4223-5. doi: 10.1182/blood-2004-10-3892. Epub 2005 Feb 17. Blood. 2005. PMID: 15718422 Free article.

Incidence of additional genetic changes in the TEL and AML1 genes in DCOG and COALL-treated t(12;21)-positive pediatric ALL, and their relation with drug sensitivity and clinical outcome.

Stams WA, Beverloo HB, den Boer ML, de Menezes RX, Stigter RL, van Drunen E, Ramakers-van-Woerden NL, Loonen AH, van Wering ER, Janka-Schaub GE, Pieters R. Stams WA, et al. Leukemia. 2006 Mar;20(3):410-6. doi: 10.1038/sj.leu.2404083. Leukemia. 2006. PMID: 16424874

Sensitivity to L-asparaginase is not associated with expression levels of asparagine synthetase in t(12;21)+ pediatric ALL.

Stams WA, den Boer ML, Beverloo HB, Meijerink JP, Stigter RL, van Wering ER, Janka-Schaub GE, Slater R, Pieters R. Stams WA, et al. Blood. 2003 Apr 1;101(7):2743-7. doi: 10.1182/blood-2002-08-2446. Epub 2002 Nov 14. Blood. 2003. PMID: 12433682 Free article.

Expression levels of TEL, AML1, and the fusion products TEL-AML1 and AML1-TEL versus drug sensitivity and clinical outcome in t(12;21)-positive pediatric acute lymphoblastic leukemia.

Stams WA, den Boer ML, Beverloo HB, Meijerink JP, van Wering ER, Janka-Schaub GE, Pieters R. Stams WA, et al. Clin Cancer Res. 2005 Apr 15;11(8):2974-80. doi: 10.1158/1078-0432.CCR-04-1829. Clin Cancer Res. 2005. PMID: 15837750

Effect of the histone deacetylase inhibitor depsipeptide on B-cell differentiation in both TEL-AML1-positive and negative childhood acute lymphoblastic leukemia.

Stams WA, den Boer ML, Beverloo HB, Kazemier KM, van Wering ER, Janka-Schaub GE, Pieters R. Stams WA, et al. Haematologica. 2005 Dec;90(12):1697-9. Haematologica. 2005. PMID: 16330447

Upregulation of asparagine synthetase and cell cycle arrest in t(12;21)-positive ALL.

Stams WA, den Boer ML, Beverloo HB, van Wering ER, Pieters R. Stams WA, et al. Leukemia. 2005 Feb;19(2):318-9; author reply 319-21. doi: 10.1038/sj.leu.2403573. Leukemia. 2005. PMID: 15526023 No abstract available.

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