Varady J - Search Results

1

Design, synthesis and structure-activity relationship studies of hexahydropyrazinoquinolines as a novel class of potent and selective dopamine receptor 3 (D3) ligands.

Ji M, Chen J, Ding K, Wu X, Varady J, Levant B, Wang S. Ji M, et al. Among authors: varady j. Bioorg Med Chem Lett. 2005 Mar 15;15(6):1701-5. doi: 10.1016/j.bmcl.2005.01.037. Bioorg Med Chem Lett. 2005. PMID: 15745825

2

Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach.

Varady J, Wu X, Fang X, Min J, Hu Z, Levant B, Wang S. Varady J, et al. J Med Chem. 2003 Oct 9;46(21):4377-92. doi: 10.1021/jm030085p. J Med Chem. 2003. PMID: 14521403

3

Design, synthesis, and evaluation of hexahydrobenz[f]isoquinolines as a novel class of dopamine 3 receptor ligands.

Wu X, Chen J, Ji M, Varady J, Levant B, Wang S. Wu X, et al. Among authors: varady j. Bioorg Med Chem Lett. 2004 Dec 6;14(23):5813-6. doi: 10.1016/j.bmcl.2004.09.047. Bioorg Med Chem Lett. 2004. PMID: 15501046

4

Enantiomerically pure hexahydropyrazinoquinolines as potent and selective dopamine 3 subtype receptor ligands.

Ding K, Chen J, Ji M, Wu X, Varady J, Yang CY, Lu Y, Deschamps JR, Levant B, Wang S. Ding K, et al. Among authors: varady j. J Med Chem. 2005 May 5;48(9):3171-81. doi: 10.1021/jm049031l. J Med Chem. 2005. PMID: 15857123

5

Structure-based discovery of nonpeptidic small organic compounds to block the T cell response to myelin basic protein.

Koehler NK, Yang CY, Varady J, Lu Y, Wu XW, Liu M, Yin D, Bartels M, Xu BY, Roller PP, Long YQ, Li P, Kattah M, Cohn ML, Moran K, Tilley E, Richert JR, Wang S. Koehler NK, et al. Among authors: varady j. J Med Chem. 2004 Oct 7;47(21):4989-97. doi: 10.1021/jm030362s. J Med Chem. 2004. PMID: 15456243

6

Structural basis of binding of high-affinity ligands to protein kinase C: prediction of the binding modes through a new molecular dynamics method and evaluation by site-directed mutagenesis.

Pak Y, Enyedy IJ, Varady J, Kung JW, Lorenzo PS, Blumberg PM, Wang S. Pak Y, et al. Among authors: varady j. J Med Chem. 2001 May 24;44(11):1690-701. doi: 10.1021/jm000488e. J Med Chem. 2001. PMID: 11356104

7

Functional preference of the constituent amino acid residues in a phage-library-based nonphosphorylated inhibitor of the Grb2-SH2 domain.

Lung FD, Long YQ, Roller PP, King CR, Varady J, Wu XW, Wang S. Lung FD, et al. Among authors: varady j. J Pept Res. 2001 Jun;57(6):447-54. doi: 10.1034/j.1399-3011.2001.00833.x. J Pept Res. 2001. PMID: 11437948

8

Molecular dynamics simulations of beta-hairpin folding.

Wang H, Varady J, Ng L, Sung SS. Wang H, et al. Among authors: varady j. Proteins. 1999 Nov 15;37(3):325-33. doi: 10.1002/(sici)1097-0134(19991115)37:3<325::aid-prot2>3.0.co;2-e. Proteins. 1999. PMID: 10591094

9

Effects of two different dexamethasone dosing regimens on ventilator-free days and long-term mortality in COVID-19 patients with moderate-to-severe ARDS: the REMED randomized clinical trial.

Maláska J, Stašek J, Máca J, Kutěj M, Duška F, Kafka P, Klementová O, Doubravská L, Hruda J, Fencl M, Gabrhelík T, Číž L, Zatloukal J, Pouska J, Novotný P, Balík M, Demlová R, Kubátová J, Vinklerová J, Grodová K, Štěpánová R, Svobodník A, Kratochvíl M, Klučka J, Štourač P, Singer M; REMED Study Group. Maláska J, et al. Eur J Med Res. 2024 Dec 23;29(1):616. doi: 10.1186/s40001-024-02215-6. Eur J Med Res. 2024. PMID: 39710693 Free PMC article. Clinical Trial.

10

Effect of dexamethasone in patients with ARDS and COVID-19 - prospective, multi-centre, open-label, parallel-group, randomised controlled trial (REMED trial): A structured summary of a study protocol for a randomised controlled trial.

Maláska J, Stašek J, Duška F, Balík M, Máca J, Hruda J, Vymazal T, Klementová O, Zatloukal J, Gabrhelík T, Novotný P, Demlová R, Kubátová J, Vinklerová J, Svobodník A, Kratochvíl M, Klučka J, Gál R, Singer M; REMED Study Group. Maláska J, et al. Trials. 2021 Mar 1;22(1):172. doi: 10.1186/s13063-021-05116-9. Trials. 2021. PMID: 33648568 Free PMC article.

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