Wang Y - Search Results

1

Further studies on ethenyl and ethynyl-4-phenylamino-3-quinolinecarbonitriles: identification of a subnanomolar Src kinase inhibitor.

Barrios Sosa AC, Boschelli DH, Wu B, Wang Y, Golas JM. Barrios Sosa AC, et al. Among authors: wang y. Bioorg Med Chem Lett. 2005 Mar 15;15(6):1743-7. doi: 10.1016/j.bmcl.2005.01.004. Bioorg Med Chem Lett. 2005. PMID: 15745832

2

Synthesis and Src kinase inhibitory activity of 2-phenyl- and 2-thienyl-7-phenylaminothieno[3,2-b]pyridine-6-carbonitriles.

Boschelli DH, Wu B, Barrios Sosa AC, Durutlic H, Chen JJ, Wang Y, Golas JM, Lucas J, Boschelli F. Boschelli DH, et al. Among authors: wang y. J Med Chem. 2005 Jun 2;48(11):3891-902. doi: 10.1021/jm050175p. J Med Chem. 2005. PMID: 15916442

3

Synthesis and Src kinase inhibitory activity of a series of 4-[(2,4-dichloro-5-methoxyphenyl)amino]-7-furyl-3-quinolinecarbonitriles.

Boschelli DH, Wu B, Ye F, Wang Y, Golas JM, Lucas J, Boschelli F. Boschelli DH, et al. Among authors: wang y. J Med Chem. 2006 Dec 28;49(26):7868-76. doi: 10.1021/jm061031t. J Med Chem. 2006. PMID: 17181170

4

First generation 5-vinyl-3-pyridinecarbonitrile PKCtheta inhibitors.

Niu C, Boschelli DH, Tumey LN, Bhagirath N, Subrath J, Shim J, Wang Y, Wu B, Eid C, Lee J, Yang X, Brennan A, Chaudhary D. Niu C, et al. Among authors: wang y. Bioorg Med Chem Lett. 2009 Oct 15;19(20):5829-32. doi: 10.1016/j.bmcl.2009.08.086. Epub 2009 Aug 29. Bioorg Med Chem Lett. 2009. PMID: 19762237

5

Optimization of 5-vinylaryl-3-pyridinecarbonitriles as PKCtheta inhibitors.

Boschelli DH, Subrath J, Niu C, Wu B, Wang Y, Lee J, Brennan A, Ho M, Deng B, Yang X, Xu X, Leung L, Wang J, Atherton J, Chaudhary D. Boschelli DH, et al. Among authors: wang j, wang y. Bioorg Med Chem Lett. 2010 Mar 15;20(6):1965-8. doi: 10.1016/j.bmcl.2010.01.119. Epub 2010 Jan 28. Bioorg Med Chem Lett. 2010. PMID: 20153643

6

Optimization of 7-alkene-3-quinolinecarbonitriles as Src kinase inhibitors.

Boschelli DH, Wang D, Wang Y, Wu B, Honores EE, Barrios Sosa AC, Chaudhary I, Golas J, Lucas J, Boschelli F. Boschelli DH, et al. Among authors: wang y, wang d. Bioorg Med Chem Lett. 2010 May 1;20(9):2924-7. doi: 10.1016/j.bmcl.2010.03.025. Epub 2010 Mar 7. Bioorg Med Chem Lett. 2010. PMID: 20363128

7

1,2,3-Thiadiazole thioacetanilides as a novel class of potent HIV-1 non-nucleoside reverse transcriptase inhibitors.

Zhan P, Liu X, Cao Y, Wang Y, Pannecouque C, De Clercq E. Zhan P, et al. Among authors: wang y. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5368-71. doi: 10.1016/j.bmcl.2008.09.055. Epub 2008 Sep 18. Bioorg Med Chem Lett. 2008. PMID: 18824350

8

Novel and potent transforming growth factor beta type I receptor kinase domain inhibitor: 7-amino 4-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-quinolines.

Li HY, Wang Y, Yan L, Campbell RM, Anderson BD, Wagner JR, Yingling JM. Li HY, et al. Among authors: wang y. Bioorg Med Chem Lett. 2004 Jul 5;14(13):3585-8. doi: 10.1016/j.bmcl.2004.04.065. Bioorg Med Chem Lett. 2004. PMID: 15177480

9

Discovery of pyrazolo[1,5-a]pyrimidine-based Pim inhibitors: a template-based approach.

Dwyer MP, Keertikar K, Paruch K, Alvarez C, Labroli M, Poker C, Fischmann TO, Mayer-Ezell R, Bond R, Wang Y, Azevedo R, Guzi TJ. Dwyer MP, et al. Among authors: wang y. Bioorg Med Chem Lett. 2013 Nov 15;23(22):6178-82. doi: 10.1016/j.bmcl.2013.08.110. Epub 2013 Sep 7. Bioorg Med Chem Lett. 2013. PMID: 24091081

10

Optimization of a dihydropyrrolopyrazole series of transforming growth factor-beta type I receptor kinase domain inhibitors: discovery of an orally bioavailable transforming growth factor-beta receptor type I inhibitor as antitumor agent.

Li HY, McMillen WT, Heap CR, McCann DJ, Yan L, Campbell RM, Mundla SR, King CH, Dierks EA, Anderson BD, Britt KS, Huss KL, Voss MD, Wang Y, Clawson DK, Yingling JM, Sawyer JS. Li HY, et al. Among authors: wang y. J Med Chem. 2008 Apr 10;51(7):2302-6. doi: 10.1021/jm701199p. Epub 2008 Mar 4. J Med Chem. 2008. PMID: 18314943

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