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Mutation analysis of three genes encoding novel LKB1-interacting proteins, BRG1, STRADalpha, and MO25alpha, in Peutz-Jeghers syndrome.
Alhopuro P, Katajisto P, Lehtonen R, Ylisaukko-Oja SK, Näätsaari L, Karhu A, Westerman AM, Wilson JH, de Rooij FW, Vogel T, Moeslein G, Tomlinson IP, Aaltonen LA, Mäkelä TP, Launonen V. Alhopuro P, et al. Among authors: westerman am. Br J Cancer. 2005 Mar 28;92(6):1126-9. doi: 10.1038/sj.bjc.6602454. Br J Cancer. 2005. PMID: 15756273 Free PMC article.
Frequency and spectrum of cancers in the Peutz-Jeghers syndrome.
Hearle N, Schumacher V, Menko FH, Olschwang S, Boardman LA, Gille JJ, Keller JJ, Westerman AM, Scott RJ, Lim W, Trimbath JD, Giardiello FM, Gruber SB, Offerhaus GJ, de Rooij FW, Wilson JH, Hansmann A, Möslein G, Royer-Pokora B, Vogel T, Phillips RK, Spigelman AD, Houlston RS. Hearle N, et al. Among authors: westerman am. Clin Cancer Res. 2006 May 15;12(10):3209-15. doi: 10.1158/1078-0432.CCR-06-0083. Clin Cancer Res. 2006. PMID: 16707622 Free article.
LKB1 exonic and whole gene deletions are a common cause of Peutz-Jeghers syndrome.
Volikos E, Robinson J, Aittomäki K, Mecklin JP, Järvinen H, Westerman AM, de Rooji FW, Vogel T, Moeslein G, Launonen V, Tomlinson IP, Silver AR, Aaltonen LA. Volikos E, et al. Among authors: westerman am. J Med Genet. 2006 May;43(5):e18. doi: 10.1136/jmg.2005.039875. J Med Genet. 2006. PMID: 16648371 Free PMC article.
Peutz-Jeghers syndrome: 78-year follow-up of the original family.
Westerman AM, Entius MM, de Baar E, Boor PP, Koole R, van Velthuysen ML, Offerhaus GJ, Lindhout D, de Rooij FW, Wilson JH. Westerman AM, et al. Lancet. 1999 Apr 10;353(9160):1211-5. doi: 10.1016/s0140-6736(98)08018-0. Lancet. 1999. PMID: 10217080
Novel mutations in the LKB1/STK11 gene in Dutch Peutz-Jeghers families.
Westerman AM, Entius MM, Boor PP, Koole R, de Baar E, Offerhaus GJ, Lubinski J, Lindhout D, Halley DJ, de Rooij FW, Wilson JH. Westerman AM, et al. Hum Mutat. 1999;13(6):476-81. doi: 10.1002/(SICI)1098-1004(1999)13:6<476::AID-HUMU7>3.0.CO;2-2. Hum Mutat. 1999. PMID: 10408777
STK11 status and intussusception risk in Peutz-Jeghers syndrome.
Hearle N, Schumacher V, Menko FH, Olschwang S, Boardman LA, Gille JJ, Keller JJ, Westerman AM, Scott RJ, Lim W, Trimbath JD, Giardiello FM, Gruber SB, Offerhaus GJ, Rooij FW, Wilson JH, Hansmann A, Möslein G, Royer-Pokora B, Vogel T, Phillips RK, Spigelman AD, Houlston RS. Hearle N, et al. Among authors: westerman am. J Med Genet. 2006 Aug;43(8):e41. doi: 10.1136/jmg.2005.040535. J Med Genet. 2006. PMID: 16882735 Free PMC article.
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