Chari R - Search Results

1

The role of halogen substitution in classical cannabinoids: a CB1 pharmacophore model.

Nikas SP, Grzybowska J, Papahatjis DP, Charalambous A, Banijamali AR, Chari R, Fan P, Kourouli T, Lin S, Nitowski AJ, Marciniak G, Guo Y, Li X, Wang CL, Makriyannis A. Nikas SP, et al. Among authors: chari r. AAPS J. 2004 Oct 19;6(4):e30. doi: 10.1208/aapsj060430. AAPS J. 2004. PMID: 15760095 Free PMC article.

2

Pharmacophoric requirements for the cannabinoid side chain. Probing the cannabinoid receptor subsite at C1'.

Papahatjis DP, Nikas SP, Kourouli T, Chari R, Xu W, Pertwee RG, Makriyannis A. Papahatjis DP, et al. Among authors: chari r. J Med Chem. 2003 Jul 17;46(15):3221-9. doi: 10.1021/jm020558c. J Med Chem. 2003. PMID: 12852753

3

Magnetically aligned bicelles to study the orientation of lipophilic ligands in membrane bilayers.

Guo J, Yang DP, Chari R, Tian X, Pavlopoulos S, Lu D, Makriyannis A. Guo J, et al. Among authors: chari r. J Med Chem. 2008 Nov 13;51(21):6793-9. doi: 10.1021/jm800766x. Epub 2008 Oct 4. J Med Chem. 2008. PMID: 18834109 Free PMC article.

4

Tumor-specific novel taxoid-monoclonal antibody conjugates.

Ojima I, Geng X, Wu X, Qu C, Borella CP, Xie H, Wilhelm SD, Leece BA, Bartle LM, Goldmacher VS, Chari RV. Ojima I, et al. J Med Chem. 2002 Dec 19;45(26):5620-3. doi: 10.1021/jm025540g. J Med Chem. 2002. PMID: 12477344

5

Semisynthetic maytansine analogues for the targeted treatment of cancer.

Widdison WC, Wilhelm SD, Cavanagh EE, Whiteman KR, Leece BA, Kovtun Y, Goldmacher VS, Xie H, Steeves RM, Lutz RJ, Zhao R, Wang L, Blättler WA, Chari RV. Widdison WC, et al. Among authors: chari rv. J Med Chem. 2006 Jul 13;49(14):4392-408. doi: 10.1021/jm060319f. J Med Chem. 2006. PMID: 16821799

6

Long- and short-range electrostatic interactions affect the rheology of highly concentrated antibody solutions.

Chari R, Jerath K, Badkar AV, Kalonia DS. Chari R, et al. Pharm Res. 2009 Dec;26(12):2607-18. doi: 10.1007/s11095-009-9975-2. Epub 2009 Oct 1. Pharm Res. 2009. PMID: 19795191

7

Development of improved empirical models for estimating the binding constant of a beta-cyclodextrin inclusion complex.

Chari R, Qureshi F, Moschera J, Tarantino R, Kalonia D. Chari R, et al. Pharm Res. 2009 Jan;26(1):161-71. doi: 10.1007/s11095-008-9733-x. Epub 2008 Oct 9. Pharm Res. 2009. PMID: 18843449

8

Synthesis and evaluation of hydrophilic linkers for antibody-maytansinoid conjugates.

Zhao RY, Wilhelm SD, Audette C, Jones G, Leece BA, Lazar AC, Goldmacher VS, Singh R, Kovtun Y, Widdison WC, Lambert JM, Chari RV. Zhao RY, et al. Among authors: chari rv. J Med Chem. 2011 May 26;54(10):3606-23. doi: 10.1021/jm2002958. Epub 2011 May 4. J Med Chem. 2011. PMID: 21517041

9

Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of cancer.

Zhao RY, Erickson HK, Leece BA, Reid EE, Goldmacher VS, Lambert JM, Chari RV. Zhao RY, et al. J Med Chem. 2012 Jan 26;55(2):766-82. doi: 10.1021/jm201284m. Epub 2012 Jan 5. J Med Chem. 2012. PMID: 22148292

10

Ado-trastuzumab Emtansine (T-DM1): an antibody-drug conjugate (ADC) for HER2-positive breast cancer.

Lambert JM, Chari RV. Lambert JM, et al. J Med Chem. 2014 Aug 28;57(16):6949-64. doi: 10.1021/jm500766w. Epub 2014 Jul 10. J Med Chem. 2014. PMID: 24967516

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