Davis MD - Search Results

1

Sphingosine-1-phosphate prevents tumor necrosis factor-{alpha}-mediated monocyte adhesion to aortic endothelium in mice.

Bolick DT, Srinivasan S, Kim KW, Hatley ME, Clemens JJ, Whetzel A, Ferger N, Macdonald TL, Davis MD, Tsao PS, Lynch KR, Hedrick CC. Bolick DT, et al. Among authors: davis md. Arterioscler Thromb Vasc Biol. 2005 May;25(5):976-81. doi: 10.1161/01.ATV.0000162171.30089.f6. Epub 2005 Mar 10. Arterioscler Thromb Vasc Biol. 2005. PMID: 15761190

2

Synthesis of para-alkyl aryl amide analogues of sphingosine-1-phosphate: discovery of potent S1P receptor agonists.

Clemens JJ, Davis MD, Lynch KR, Macdonald TL. Clemens JJ, et al. Among authors: davis md. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3401-4. doi: 10.1016/s0960-894x(03)00812-6. Bioorg Med Chem Lett. 2003. PMID: 14505636

3

Synthesis of benzimidazole based analogues of sphingosine-1-phosphate: discovery of potent, subtype-selective S1P4 receptor agonists.

Clemens JJ, Davis MD, Lynch KR, Macdonald TL. Clemens JJ, et al. Among authors: davis md. Bioorg Med Chem Lett. 2004 Oct 4;14(19):4903-6. doi: 10.1016/j.bmcl.2004.07.030. Bioorg Med Chem Lett. 2004. PMID: 15341948

4

Sphingosine 1-phosphate analogs as receptor antagonists.

Davis MD, Clemens JJ, Macdonald TL, Lynch KR. Davis MD, et al. J Biol Chem. 2005 Mar 18;280(11):9833-41. doi: 10.1074/jbc.M412356200. Epub 2004 Dec 8. J Biol Chem. 2005. PMID: 15590668 Free article.

5

Synthesis of 4(5)-phenylimidazole-based analogues of sphingosine-1-phosphate and FTY720: discovery of potent S1P1 receptor agonists.

Clemens JJ, Davis MD, Lynch KR, Macdonald TL. Clemens JJ, et al. Among authors: davis md. Bioorg Med Chem Lett. 2005 Aug 1;15(15):3568-72. doi: 10.1016/j.bmcl.2005.05.097. Bioorg Med Chem Lett. 2005. PMID: 15982878

6

Synthesis, stability, and implications of phosphothioate agonists of sphingosine-1-phosphate receptors.

Foss FW Jr, Clemens JJ, Davis MD, Snyder AH, Zigler MA, Lynch KR, Macdonald TL. Foss FW Jr, et al. Among authors: davis md. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4470-4. doi: 10.1016/j.bmcl.2005.07.057. Bioorg Med Chem Lett. 2005. PMID: 16125386

7

Synthesis and biological evaluation of gamma-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists.

Foss FW Jr, Snyder AH, Davis MD, Rouse M, Okusa MD, Lynch KR, Macdonald TL. Foss FW Jr, et al. Among authors: davis md. Bioorg Med Chem. 2007 Jan 15;15(2):663-77. doi: 10.1016/j.bmc.2006.10.060. Epub 2006 Nov 1. Bioorg Med Chem. 2007. PMID: 17113298 Free PMC article.

8

Synthesis and biological evaluation of sphingosine kinase substrates as sphingosine-1-phosphate receptor prodrugs.

Foss FW Jr, Mathews TP, Kharel Y, Kennedy PC, Snyder AH, Davis MD, Lynch KR, Macdonald TL. Foss FW Jr, et al. Among authors: davis md. Bioorg Med Chem. 2009 Aug 15;17(16):6123-36. doi: 10.1016/j.bmc.2009.04.015. Epub 2009 Apr 12. Bioorg Med Chem. 2009. PMID: 19632123 Free PMC article.

9

The immune modulator FTY720 targets sphingosine 1-phosphate receptors.

Brinkmann V, Davis MD, Heise CE, Albert R, Cottens S, Hof R, Bruns C, Prieschl E, Baumruker T, Hiestand P, Foster CA, Zollinger M, Lynch KR. Brinkmann V, et al. Among authors: davis md. J Biol Chem. 2002 Jun 14;277(24):21453-7. doi: 10.1074/jbc.C200176200. Epub 2002 Apr 19. J Biol Chem. 2002. PMID: 11967257 Free article.

10

B lymphocytes exit lymph nodes through cortical lymphatic sinusoids by a mechanism independent of sphingosine-1-phosphate-mediated chemotaxis.

Sinha RK, Park C, Hwang IY, Davis MD, Kehrl JH. Sinha RK, et al. Among authors: davis md. Immunity. 2009 Mar 20;30(3):434-46. doi: 10.1016/j.immuni.2008.12.018. Epub 2009 Feb 19. Immunity. 2009. PMID: 19230723 Free PMC article.

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