Portoghese PS - Search Results

1

Homology modeling and molecular dynamics simulations of the mu opioid receptor in a membrane-aqueous system.

Zhang Y, Sham YY, Rajamani R, Gao J, Portoghese PS. Zhang Y, et al. Among authors: portoghese ps. Chembiochem. 2005 May;6(5):853-9. doi: 10.1002/cbic.200400207. Chembiochem. 2005. PMID: 15776407

2

Specific cross-linking of Lys233 and Cys235 in the mu opioid receptor by a reporter affinity label.

Zhang Y, McCurdy CR, Metzger TG, Portoghese PS. Zhang Y, et al. Among authors: portoghese ps. Biochemistry. 2005 Feb 22;44(7):2271-5. doi: 10.1021/bi048049v. Biochemistry. 2005. PMID: 15709739

3

Inhibition of Inflammatory and Neuropathic Pain by Targeting a Mu Opioid Receptor/Chemokine Receptor5 Heteromer (MOR-CCR5).

Akgün E, Javed MI, Lunzer MM, Powers MD, Sham YY, Watanabe Y, Portoghese PS. Akgün E, et al. Among authors: portoghese ps. J Med Chem. 2015 Nov 12;58(21):8647-57. doi: 10.1021/acs.jmedchem.5b01245. Epub 2015 Oct 20. J Med Chem. 2015. PMID: 26451468 Free PMC article.

4

Naphthalene dicarboxaldehyde as an electrophilic fluorogenic moiety for affinity labeling: application to opioid receptor affinity labels with greatly improved fluorogenic properties.

McCurdy CR, Le Bourdonnec B, Metzger TG, El Kouhen R, Zhang Y, Law PY, Portoghese PS. McCurdy CR, et al. Among authors: portoghese ps. J Med Chem. 2002 Jul 4;45(14):2887-90. doi: 10.1021/jm015586u. J Med Chem. 2002. PMID: 12086475

5

o-Naphthalenedicarboxaldehyde derivative of 7'-aminonaltrindole as a selective delta-opioid receptor affinity label.

Haris SP, Zhang Y, Le Bourdonnec B, McCurdy CR, Portoghese PS. Haris SP, et al. Among authors: portoghese ps. J Med Chem. 2007 Jul 12;50(14):3392-6. doi: 10.1021/jm061194h. Epub 2007 Jun 8. J Med Chem. 2007. PMID: 17555306

6

An immunocytochemical-derived correlate for evaluating the bridging of heteromeric mu-delta opioid protomers by bivalent ligands.

Yekkirala AS, Kalyuzhny AE, Portoghese PS. Yekkirala AS, et al. Among authors: portoghese ps. ACS Chem Biol. 2013 Jul 19;8(7):1412-6. doi: 10.1021/cb400113d. Epub 2013 May 17. ACS Chem Biol. 2013. PMID: 23675763 Free PMC article.

7

Molecular docking reveals a novel binding site model for fentanyl at the mu-opioid receptor.

Subramanian G, Paterlini MG, Portoghese PS, Ferguson DM. Subramanian G, et al. Among authors: portoghese ps. J Med Chem. 2000 Feb 10;43(3):381-91. doi: 10.1021/jm9903702. J Med Chem. 2000. PMID: 10669565

8

A bivalent ligand (KMN-21) antagonist for mu/kappa heterodimeric opioid receptors.

Zhang S, Yekkirala A, Tang Y, Portoghese PS. Zhang S, et al. Among authors: portoghese ps. Bioorg Med Chem Lett. 2009 Dec 15;19(24):6978-80. doi: 10.1016/j.bmcl.2009.10.045. Epub 2009 Nov 4. Bioorg Med Chem Lett. 2009. PMID: 19892550 Free PMC article.

9

Identity of the putative delta1-opioid receptor as a delta-kappa heteromer in the mouse spinal cord.

Portoghese PS, Lunzer MM. Portoghese PS, et al. Eur J Pharmacol. 2003 Apr 25;467(1-3):233-4. doi: 10.1016/s0014-2999(03)01599-1. Eur J Pharmacol. 2003. PMID: 12706480

10

Effect of opioid receptor ligands on the mu-S196A knock-in and mu knockout mouse vas deferens.

Portoghese PS, Law PY, Loh HH. Portoghese PS, et al. Eur J Pharmacol. 2003 Oct 8;478(2-3):207-10. doi: 10.1016/j.ejphar.2003.08.041. Eur J Pharmacol. 2003. PMID: 14575806

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