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Gβγ directly modulates vesicle fusion by competing with synaptotagmin for binding to neuronal SNARE proteins embedded in membranes.
Zurawski Z, Page B, Chicka MC, Brindley RL, Wells CA, Preininger AM, Hyde K, Gilbert JA, Cruz-Rodriguez O, Currie KPM, Chapman ER, Alford S, Hamm HE. Zurawski Z, et al. Among authors: preininger am. J Biol Chem. 2017 Jul 21;292(29):12165-12177. doi: 10.1074/jbc.M116.773523. Epub 2017 May 17. J Biol Chem. 2017. PMID: 28515322 Free PMC article.
Insights into G protein structure, function, and regulation.
Cabrera-Vera TM, Vanhauwe J, Thomas TO, Medkova M, Preininger A, Mazzoni MR, Hamm HE. Cabrera-Vera TM, et al. Endocr Rev. 2003 Dec;24(6):765-81. doi: 10.1210/er.2000-0026. Endocr Rev. 2003. PMID: 14671004 Review.
Direct modulation of phospholipase D activity by Gbetagamma.
Preininger AM, Henage LG, Oldham WM, Yoon EJ, Hamm HE, Brown HA. Preininger AM, et al. Mol Pharmacol. 2006 Jul;70(1):311-8. doi: 10.1124/mol.105.021451. Epub 2006 Apr 25. Mol Pharmacol. 2006. PMID: 16638972
36 results