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The propeptide mediates formation of stromal stores of PROMIC-1: role in determining prostate cancer outcome.
Bauskin AR, Brown DA, Junankar S, Rasiah KK, Eggleton S, Hunter M, Liu T, Smith D, Kuffner T, Pankhurst GJ, Johnen H, Russell PJ, Barret W, Stricker PD, Grygiel JJ, Kench JG, Henshall SM, Sutherland RL, Breit SN. Bauskin AR, et al. Among authors: breit sn. Cancer Res. 2005 Mar 15;65(6):2330-6. doi: 10.1158/0008-5472.CAN-04-3827. Cancer Res. 2005. PMID: 15781647
MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily.
Bootcov MR, Bauskin AR, Valenzuela SM, Moore AG, Bansal M, He XY, Zhang HP, Donnellan M, Mahler S, Pryor K, Walsh BJ, Nicholson RC, Fairlie WD, Por SB, Robbins JM, Breit SN. Bootcov MR, et al. Among authors: breit sn. Proc Natl Acad Sci U S A. 1997 Oct 14;94(21):11514-9. doi: 10.1073/pnas.94.21.11514. Proc Natl Acad Sci U S A. 1997. PMID: 9326641 Free PMC article.
The propeptide of the transforming growth factor-beta superfamily member, macrophage inhibitory cytokine-1 (MIC-1), is a multifunctional domain that can facilitate protein folding and secretion.
Fairlie WD, Zhang HP, Wu WM, Pankhurst SL, Bauskin AR, Russell PK, Brown PK, Breit SN. Fairlie WD, et al. Among authors: breit sn. J Biol Chem. 2001 May 18;276(20):16911-8. doi: 10.1074/jbc.M010000200. Epub 2001 Feb 26. J Biol Chem. 2001. PMID: 11278594 Free article.
Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-A resolution.
Harrop SJ, DeMaere MZ, Fairlie WD, Reztsova T, Valenzuela SM, Mazzanti M, Tonini R, Qiu MR, Jankova L, Warton K, Bauskin AR, Wu WM, Pankhurst S, Campbell TJ, Breit SN, Curmi PM. Harrop SJ, et al. Among authors: breit sn. J Biol Chem. 2001 Nov 30;276(48):44993-5000. doi: 10.1074/jbc.M107804200. Epub 2001 Sep 10. J Biol Chem. 2001. PMID: 11551966 Free article.
170 results