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The development of atypical haemolytic-uraemic syndrome is influenced by susceptibility factors in factor H and membrane cofactor protein: evidence from two independent cohorts.
Fremeaux-Bacchi V, Kemp EJ, Goodship JA, Dragon-Durey MA, Strain L, Loirat C, Deng HW, Goodship TH. Fremeaux-Bacchi V, et al. Among authors: goodship ja, goodship th. J Med Genet. 2005 Nov;42(11):852-6. doi: 10.1136/jmg.2005.030783. Epub 2005 Mar 22. J Med Genet. 2005. PMID: 15784724 Free PMC article.
Factors determining penetrance in familial atypical haemolytic uraemic syndrome.
Sansbury FH, Cordell HJ, Bingham C, Bromilow G, Nicholls A, Powell R, Shields B, Smyth L, Warwicker P, Strain L, Wilson V, Goodship JA, Goodship TH, Turnpenny PD. Sansbury FH, et al. Among authors: goodship ja. J Med Genet. 2014 Nov;51(11):756-64. doi: 10.1136/jmedgenet-2014-102498. Epub 2014 Sep 26. J Med Genet. 2014. PMID: 25261570
Does complement factor B have a role in the pathogenesis of atypical HUS?
Kavanagh D, Kemp EJ, Richards A, Burgess RM, Mayland E, Goodship JA, Goodship TH. Kavanagh D, et al. Among authors: goodship ja, goodship th. Mol Immunol. 2006 Mar;43(7):856-9. doi: 10.1016/j.molimm.2005.06.041. Epub 2005 Aug 2. Mol Immunol. 2006. PMID: 16061287
De novo gene conversion in the RCA gene cluster (1q32) causes mutations in complement factor H associated with atypical hemolytic uremic syndrome.
Heinen S, Sanchez-Corral P, Jackson MS, Strain L, Goodship JA, Kemp EJ, Skerka C, Jokiranta TS, Meyers K, Wagner E, Robitaille P, Esparza-Gordillo J, Rodriguez de Cordoba S, Zipfel PF, Goodship TH. Heinen S, et al. Among authors: goodship ja, goodship th. Hum Mutat. 2006 Mar;27(3):292-3. doi: 10.1002/humu.9408. Hum Mutat. 2006. PMID: 16470555
Atypical haemolytic uraemic syndrome associated with a hybrid complement gene.
Venables JP, Strain L, Routledge D, Bourn D, Powell HM, Warwicker P, Diaz-Torres ML, Sampson A, Mead P, Webb M, Pirson Y, Jackson MS, Hughes A, Wood KM, Goodship JA, Goodship TH. Venables JP, et al. Among authors: goodship ja, goodship th. PLoS Med. 2006 Oct;3(10):e431. doi: 10.1371/journal.pmed.0030431. PLoS Med. 2006. PMID: 17076561 Free PMC article.
Deletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndrome.
Zipfel PF, Edey M, Heinen S, Józsi M, Richter H, Misselwitz J, Hoppe B, Routledge D, Strain L, Hughes AE, Goodship JA, Licht C, Goodship TH, Skerka C. Zipfel PF, et al. Among authors: goodship ja, goodship th. PLoS Genet. 2007 Mar 16;3(3):e41. doi: 10.1371/journal.pgen.0030041. Epub 2007 Feb 1. PLoS Genet. 2007. PMID: 17367211 Free PMC article.
Factor H--US?
Warwicker P, Goodship JA, Goodship TH. Warwicker P, et al. Among authors: goodship ja, goodship th. Nephrol Dial Transplant. 1998 Aug;13(8):1921-3. doi: 10.1093/ndt/13.8.1921. Nephrol Dial Transplant. 1998. PMID: 9719138 Review. No abstract available.
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