Xie T - Search Results

1

Deficiency of the G-protein alpha-subunit G(s)alpha in osteoblasts leads to differential effects on trabecular and cortical bone.

Sakamoto A, Chen M, Nakamura T, Xie T, Karsenty G, Weinstein LS. Sakamoto A, et al. Among authors: xie t. J Biol Chem. 2005 Jun 3;280(22):21369-75. doi: 10.1074/jbc.M500346200. Epub 2005 Mar 28. J Biol Chem. 2005. PMID: 15797856 Free article.

2

The alternative stimulatory G protein alpha-subunit XLalphas is a critical regulator of energy and glucose metabolism and sympathetic nerve activity in adult mice.

Xie T, Plagge A, Gavrilova O, Pack S, Jou W, Lai EW, Frontera M, Kelsey G, Weinstein LS. Xie T, et al. J Biol Chem. 2006 Jul 14;281(28):18989-99. doi: 10.1074/jbc.M511752200. Epub 2006 May 2. J Biol Chem. 2006. PMID: 16672216 Free PMC article.

3

Studies of the regulation and function of the Gs alpha gene Gnas using gene targeting technology.

Weinstein LS, Xie T, Zhang QH, Chen M. Weinstein LS, et al. Among authors: xie t. Pharmacol Ther. 2007 Aug;115(2):271-91. doi: 10.1016/j.pharmthera.2007.03.013. Epub 2007 Apr 21. Pharmacol Ther. 2007. PMID: 17588669 Free PMC article. Review.

4

Beta cell-specific deficiency of the stimulatory G protein alpha-subunit Gsalpha leads to reduced beta cell mass and insulin-deficient diabetes.

Xie T, Chen M, Zhang QH, Ma Z, Weinstein LS. Xie T, et al. Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19601-6. doi: 10.1073/pnas.0704796104. Epub 2007 Nov 20. Proc Natl Acad Sci U S A. 2007. PMID: 18029451 Free PMC article.

5

Pancreas-specific Gsalpha deficiency has divergent effects on pancreatic alpha- and beta-cell proliferation.

Xie T, Chen M, Weinstein LS. Xie T, et al. J Endocrinol. 2010 Sep;206(3):261-9. doi: 10.1677/JOE-10-0030. Epub 2010 Jun 11. J Endocrinol. 2010. PMID: 20543009 Free PMC article.

6

The role of GNAS and other imprinted genes in the development of obesity.

Weinstein LS, Xie T, Qasem A, Wang J, Chen M. Weinstein LS, et al. Among authors: xie t. Int J Obes (Lond). 2010 Jan;34(1):6-17. doi: 10.1038/ijo.2009.222. Epub 2009 Oct 20. Int J Obes (Lond). 2010. PMID: 19844212 Free PMC article. Review.

7

Minireview: GNAS: normal and abnormal functions.

Weinstein LS, Liu J, Sakamoto A, Xie T, Chen M. Weinstein LS, et al. Among authors: xie t. Endocrinology. 2004 Dec;145(12):5459-64. doi: 10.1210/en.2004-0865. Epub 2004 Aug 26. Endocrinology. 2004. PMID: 15331575 Review.

8

Alternative Gnas gene products have opposite effects on glucose and lipid metabolism.

Chen M, Gavrilova O, Liu J, Xie T, Deng C, Nguyen AT, Nackers LM, Lorenzo J, Shen L, Weinstein LS. Chen M, et al. Among authors: xie t. Proc Natl Acad Sci U S A. 2005 May 17;102(20):7386-91. doi: 10.1073/pnas.0408268102. Epub 2005 May 9. Proc Natl Acad Sci U S A. 2005. PMID: 15883378 Free PMC article.

9

Genetic diseases associated with heterotrimeric G proteins.

Weinstein LS, Chen M, Xie T, Liu J. Weinstein LS, et al. Among authors: xie t. Trends Pharmacol Sci. 2006 May;27(5):260-6. doi: 10.1016/j.tips.2006.03.005. Epub 2006 Apr 5. Trends Pharmacol Sci. 2006. PMID: 16600389 Review.

10

Severe obesity and insulin resistance due to deletion of the maternal Gsalpha allele is reversed by paternal deletion of the Gsalpha imprint control region.

Xie T, Chen M, Gavrilova O, Lai EW, Liu J, Weinstein LS. Xie T, et al. Endocrinology. 2008 May;149(5):2443-50. doi: 10.1210/en.2007-1458. Epub 2008 Jan 17. Endocrinology. 2008. PMID: 18202131 Free PMC article.

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