Araki K - Search Results

1

Identification of molecular target of AMP-activated protein kinase activator by affinity purification and mass spectrometry.

Kosaka T, Okuyama R, Sun W, Ogata T, Harada J, Araki K, Izumi M, Yoshida T, Okuno A, Fujiwara T, Ohsumi J, Ichikawa K. Kosaka T, et al. Among authors: araki k. Anal Chem. 2005 Apr 1;77(7):2050-5. doi: 10.1021/ac0484631. Anal Chem. 2005. PMID: 15801737

2

Direct comparison of in vivo antisense activity of ENA oligonucleotides targeting PTP1B mRNA with that of 2'-O-(2-methoxy)ethyl-modified oligonucleotides.

Koizumi M, Takagi-Sato M, Okuyama R, Araki K, Sun W, Nakai D, Tsutsumi S, Kawai K. Koizumi M, et al. Among authors: araki k. Oligonucleotides. 2006 Fall;16(3):253-62. doi: 10.1089/oli.2006.16.253. Oligonucleotides. 2006. PMID: 16978088

3

In vivo antisense activity of ENA oligonucleotides targeting PTP1B mRNA in comparison of that of 2'-MOE-modified oligonucleotides.

Koizumi M, Takagi-Sato M, Okuyama R, Araki K, Sun W, Nakai D. Koizumi M, et al. Among authors: araki k. Nucleic Acids Symp Ser (Oxf). 2007;(51):111-2. doi: 10.1093/nass/nrm056. Nucleic Acids Symp Ser (Oxf). 2007. PMID: 18029611

4

(-)-Cercosporamide derivatives as novel antihyperglycemic agents.

Furukawa A, Arita T, Satoh S, Araki K, Kuroha M, Ohsumi J. Furukawa A, et al. Among authors: araki k. Bioorg Med Chem Lett. 2009 Feb 1;19(3):724-6. doi: 10.1016/j.bmcl.2008.12.035. Epub 2008 Dec 11. Bioorg Med Chem Lett. 2009. PMID: 19109017

5

Potent antidiabetic effects of rivoglitazone, a novel peroxisome proliferator-activated receptor-gamma agonist, in obese diabetic rodent models.

Kanda S, Nakashima R, Takahashi K, Tanaka J, Ogawa J, Ogata T, Yachi M, Araki K, Ohsumi J. Kanda S, et al. Among authors: araki k. J Pharmacol Sci. 2009 Oct;111(2):155-66. doi: 10.1254/jphs.09084fp. Epub 2009 Oct 6. J Pharmacol Sci. 2009. PMID: 19809220 Free article.

6

Discovery of a novel selective PPARgamma modulator from (-)-Cercosporamide derivatives.

Furukawa A, Arita T, Satoh S, Wakabayashi K, Hayashi S, Matsui Y, Araki K, Kuroha M, Ohsumi J. Furukawa A, et al. Among authors: araki k. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2095-8. doi: 10.1016/j.bmcl.2010.02.073. Epub 2010 Feb 20. Bioorg Med Chem Lett. 2010. PMID: 20219371

7

Pharmacology and in vitro profiling of a novel peroxisome proliferator-activated receptor γ ligand, Cerco-A.

Wakabayashi K, Hayashi S, Matsui Y, Matsumoto T, Furukawa A, Kuroha M, Tanaka N, Inaba T, Kanda S, Tanaka J, Okuyama R, Wakimoto S, Ogata T, Araki K, Ohsumi J. Wakabayashi K, et al. Among authors: araki k. Biol Pharm Bull. 2011;34(7):1094-104. doi: 10.1248/bpb.34.1094. Biol Pharm Bull. 2011. PMID: 21720019 Free article.

8

Substituents at the naphthalene C3 position of (-)-Cercosporamide derivatives significantly affect the maximal efficacy as PPARγ partial agonists.

Furukawa A, Arita T, Fukuzaki T, Satoh S, Mori M, Honda T, Matsui Y, Wakabayashi K, Hayashi S, Araki K, Ohsumi J. Furukawa A, et al. Among authors: araki k. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1348-51. doi: 10.1016/j.bmcl.2011.12.066. Epub 2011 Dec 16. Bioorg Med Chem Lett. 2012. PMID: 22225641

9

Synthesis and biological evaluation of novel (-)-Cercosporamide derivatives as potent selective PPARγ modulators.

Furukawa A, Arita T, Fukuzaki T, Mori M, Honda T, Satoh S, Matsui Y, Wakabayashi K, Hayashi S, Nakamura K, Araki K, Kuroha M, Tanaka J, Wakimoto S, Suzuki O, Ohsumi J. Furukawa A, et al. Among authors: araki k. Eur J Med Chem. 2012 Aug;54:522-33. doi: 10.1016/j.ejmech.2012.05.040. Epub 2012 Jun 7. Eur J Med Chem. 2012. PMID: 22727448

10

Discovery of DS-6930, a potent selective PPARγ modulator. Part II: Lead optimization.

Shinozuka T, Tsukada T, Fujii K, Tokumaru E, Shimada K, Onishi Y, Matsui Y, Wakimoto S, Kuroha M, Ogata T, Araki K, Ohsumi J, Sawamura R, Watanabe N, Yamamoto H, Fujimoto K, Tani Y, Mori M, Tanaka J. Shinozuka T, et al. Among authors: araki k. Bioorg Med Chem. 2018 Oct 1;26(18):5099-5117. doi: 10.1016/j.bmc.2018.09.005. Epub 2018 Sep 8. Bioorg Med Chem. 2018. PMID: 30220602

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