Stiborová M - Search Results

1

Identification of a genotoxic mechanism for the carcinogenicity of the environmental pollutant and suspected human carcinogen o-anisidine.

Stiborová M, Miksanová M, Sulc M, Rýdlová H, Schmeiser HH, Frei E. Stiborová M, et al. Int J Cancer. 2005 Sep 20;116(5):667-78. doi: 10.1002/ijc.21122. Int J Cancer. 2005. PMID: 15828049

2

Sudan I is a potential carcinogen for humans: evidence for its metabolic activation and detoxication by human recombinant cytochrome P450 1A1 and liver microsomes.

Stiborová M, Martínek V, Rýdlová H, Hodek P, Frei E. Stiborová M, et al. Cancer Res. 2002 Oct 15;62(20):5678-84. Cancer Res. 2002. PMID: 12384524

3

DNA adduct formation by the anticancer drug ellipticine in rats determined by 32P postlabeling.

Stiborová M, Breuer A, Aimová D, Stiborová-Rupertová M, Wiessler M, Frei E. Stiborová M, et al. Among authors: stiborova rupertova m. Int J Cancer. 2003 Dec 20;107(6):885-90. doi: 10.1002/ijc.11511. Int J Cancer. 2003. PMID: 14601046

4

Identification of a genotoxic mechanism for 2-nitroanisole carcinogenicity and of its carcinogenic potential for humans.

Stiborová M, Miksanová M, Smrcek S, Bieler CA, Breuer A, Klokow KA, Schmeiser HH, Frei E. Stiborová M, et al. Carcinogenesis. 2004 May;25(5):833-40. doi: 10.1093/carcin/bgh061. Epub 2004 Jan 16. Carcinogenesis. 2004. PMID: 14729594

5

Enzymes involved in the metabolism of the carcinogen 2-nitroanisole: evidence for its oxidative detoxication by human cytochromes P450.

Miksanová M, Sulc M, Rýdlová H, Schmeiser HH, Frei E, Stiborová M. Miksanová M, et al. Among authors: stiborova m. Chem Res Toxicol. 2004 May;17(5):663-71. doi: 10.1021/tx0499721. Chem Res Toxicol. 2004. PMID: 15144223

6

Human hepatic and renal microsomes, cytochromes P450 1A1/2, NADPH:cytochrome P450 reductase and prostaglandin H synthase mediate the formation of aristolochic acid-DNA adducts found in patients with urothelial cancer.

Stiborová M, Frei E, Hodek P, Wiessler M, Schmeiser HH. Stiborová M, et al. Int J Cancer. 2005 Jan 10;113(2):189-97. doi: 10.1002/ijc.20564. Int J Cancer. 2005. PMID: 15386410

7

Expression of cytochrome P450 1A1 and its contribution to oxidation of a potential human carcinogen 1-phenylazo-2-naphthol (Sudan I) in human livers.

Stiborová M, Martínek V, Rýdlová H, Koblas T, Hodek P. Stiborová M, et al. Cancer Lett. 2005 Apr 8;220(2):145-54. doi: 10.1016/j.canlet.2004.07.036. Cancer Lett. 2005. PMID: 15766589

8

The binding of aristolochic acid I to the active site of human cytochromes P450 1A1 and 1A2 explains their potential to reductively activate this human carcinogen.

Stiborová M, Sopko B, Hodek P, Frei E, Schmeiser HH, Hudecek J. Stiborová M, et al. Cancer Lett. 2005 Nov 18;229(2):193-204. doi: 10.1016/j.canlet.2005.06.038. Epub 2005 Aug 24. Cancer Lett. 2005. PMID: 16125300

9

Molecular mechanism of genotoxicity of the environmental pollutant 3-nitrobenzanthrone.

Stiborová M, Arlt VM, Henderson CJ, Wolf CR, Frei E, Schmeiser HH, Phillips DH. Stiborová M, et al. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2005 Dec;149(2):191-7. doi: 10.5507/bp.2005.025. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2005. PMID: 16601755 Review.

10

Carcinogenic pollutants o-nitroanisole and o-anisidine are substrates and inducers of cytochromes P450.

Rýdlová H, Miksanová M, Ryslavá H, Stiborová M. Rýdlová H, et al. Among authors: stiborova m. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2005 Dec;149(2):441-7. doi: 10.5507/bp.2005.077. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2005. PMID: 16601807

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