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Page 1
Development of N-2,4-pyrimidine-N-phenyl-N'-alkyl ureas as orally active inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 2.
Maier JA, Brugel TA, Clark MP, Sabat M, Golebiowski A, Bookland RG, Laufersweiler MJ, Laughlin SK, Vanrens JC, De B, Hsieh LC, Brown KK, Juergens K, Walter RL, Janusz MJ. Maier JA, et al. Among authors: de b. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3514-8. doi: 10.1016/j.bmcl.2006.03.096. Epub 2006 Apr 24. Bioorg Med Chem Lett. 2006. PMID: 16632350
Development of N-2,4-pyrimidine-N-phenyl-N'-phenyl ureas as inhibitors of tumor necrosis factor alpha (TNF-alpha) synthesis. Part 1.
Brugel TA, Maier JA, Clark MP, Sabat M, Golebiowski A, Bookland RG, Laufersweiler MJ, Laughlin SK, Vanrens JC, De B, Hsieh LC, Mekel MJ, Janusz MJ. Brugel TA, et al. Among authors: de b. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3510-3. doi: 10.1016/j.bmcl.2006.03.095. Epub 2006 May 2. Bioorg Med Chem Lett. 2006. PMID: 16632356
Development of pyrimidine-based inhibitors of Janus tyrosine kinase 3.
Chen JJ, Thakur KD, Clark MP, Laughlin SK, George KM, Bookland RG, Davis JR, Cabrera EJ, Easwaran V, De B, George Zhang Y. Chen JJ, et al. Among authors: de b. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5633-8. doi: 10.1016/j.bmcl.2006.08.022. Epub 2006 Aug 24. Bioorg Med Chem Lett. 2006. PMID: 16934457
Development of new pyrrolopyrimidine-based inhibitors of Janus kinase 3 (JAK3).
Clark MP, George KM, Bookland RG, Chen J, Laughlin SK, Thakur KD, Lee W, Davis JR, Cabrera EJ, Brugel TA, VanRens JC, Laufersweiler MJ, Maier JA, Sabat MP, Golebiowski A, Easwaran V, Webster ME, De B, Zhang G. Clark MP, et al. Among authors: de b. Bioorg Med Chem Lett. 2007 Mar 1;17(5):1250-3. doi: 10.1016/j.bmcl.2006.12.018. Epub 2006 Dec 9. Bioorg Med Chem Lett. 2007. PMID: 17189692
459 results