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Neoadjuvant percutaneous 4-hydroxytamoxifen decreases breast tumoral cell proliferation: a prospective controlled randomized study comparing three doses of 4-hydroxytamoxifen gel to oral tamoxifen.
Rouanet P, Linares-Cruz G, Dravet F, Poujol S, Gourgou S, Simony-Lafontaine J, Grenier J, Kramar A, Girault J, Le Nestour E, Maudelonde T. Rouanet P, et al. Among authors: linares cruz g. J Clin Oncol. 2005 May 1;23(13):2980-7. doi: 10.1200/JCO.2005.06.064. J Clin Oncol. 2005. PMID: 15860853 Clinical Trial.
SIAH-1 inhibits cell growth by altering the mitotic process.
Bruzzoni-Giovanelli H, Faille A, Linares-Cruz G, Nemani M, Le Deist F, Germani A, Chassoux D, Millot G, Roperch JP, Amson R, Telerman A, Calvo F. Bruzzoni-Giovanelli H, et al. Among authors: linares cruz g. Oncogene. 1999 Nov 25;18(50):7101-9. doi: 10.1038/sj.onc.1203187. Oncogene. 1999. PMID: 10597311
p21WAF-1 reorganizes the nucleus in tumor suppression.
Linares-Cruz G, Bruzzoni-Giovanelli H, Alvaro V, Roperch JP, Tuynder M, Schoevaert D, Nemani M, Prieur S, Lethrosne F, Piouffre L, Reclar V, Faille A, Chassoux D, Dausset J, Amson RB, Calvo F, Telerman A. Linares-Cruz G, et al. Proc Natl Acad Sci U S A. 1998 Feb 3;95(3):1131-5. doi: 10.1073/pnas.95.3.1131. Proc Natl Acad Sci U S A. 1998. PMID: 9448297 Free PMC article.
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