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Systemic transforming growth factor-beta1 gene therapy induces Foxp3+ regulatory cells, restores self-tolerance, and facilitates regeneration of beta cell function in overtly diabetic nonobese diabetic mice.
Luo X, Yang H, Kim IS, Saint-Hilaire F, Thomas DA, De BP, Ozkaynak E, Muthukumar T, Hancock WW, Crystal RG, Suthanthiran M. Luo X, et al. Among authors: crystal rg. Transplantation. 2005 May 15;79(9):1091-6. doi: 10.1097/01.tp.0000161223.54452.a2. Transplantation. 2005. PMID: 15880049
AAV2-mediated CLN2 gene transfer to rodent and non-human primate brain results in long-term TPP-I expression compatible with therapy for LINCL.
Sondhi D, Peterson DA, Giannaris EL, Sanders CT, Mendez BS, De B, Rostkowski AB, Blanchard B, Bjugstad K, Sladek JR Jr, Redmond DE Jr, Leopold PL, Kaminsky SM, Hackett NR, Crystal RG. Sondhi D, et al. Among authors: crystal rg. Gene Ther. 2005 Nov;12(22):1618-32. doi: 10.1038/sj.gt.3302549. Gene Ther. 2005. PMID: 16052206
High levels of persistent expression of alpha1-antitrypsin mediated by the nonhuman primate serotype rh.10 adeno-associated virus despite preexisting immunity to common human adeno-associated viruses.
De BP, Heguy A, Hackett NR, Ferris B, Leopold PL, Lee J, Pierre L, Gao G, Wilson JM, Crystal RG. De BP, et al. Among authors: crystal rg. Mol Ther. 2006 Jan;13(1):67-76. doi: 10.1016/j.ymthe.2005.09.003. Epub 2005 Nov 2. Mol Ther. 2006. PMID: 16260185 Free article.
914 results