Kelland LR - Search Results

1

Tumor dose response to the vascular disrupting agent, 5,6-dimethylxanthenone-4-acetic acid, using in vivo magnetic resonance spectroscopy.

McPhail LD, Chung YL, Madhu B, Clark S, Griffiths JR, Kelland LR, Robinson SP. McPhail LD, et al. Among authors: kelland lr. Clin Cancer Res. 2005 May 15;11(10):3705-13. doi: 10.1158/1078-0432.CCR-04-2504. Clin Cancer Res. 2005. PMID: 15897567

2

Rat tumor response to the vascular-disrupting agent 5,6-dimethylxanthenone-4-acetic acid as measured by dynamic contrast-enhanced magnetic resonance imaging, plasma 5-hydroxyindoleacetic acid levels, and tumor necrosis.

McPhail LD, McIntyre DJ, Ludwig C, Kestell P, Griffiths JR, Kelland LR, Robinson SP. McPhail LD, et al. Among authors: kelland lr. Neoplasia. 2006 Mar;8(3):199-206. doi: 10.1593/neo.05739. Neoplasia. 2006. PMID: 16611413 Free PMC article.

3

Increased tumour extracellular pH induced by Bafilomycin A1 inhibits tumour growth and mitosis in vivo and alters 5-fluorouracil pharmacokinetics.

McSheehy PM, Troy H, Kelland LR, Judson IR, Leach MO, Griffiths JR. McSheehy PM, et al. Among authors: kelland lr. Eur J Cancer. 2003 Mar;39(4):532-40. doi: 10.1016/s0959-8049(02)00671-8. Eur J Cancer. 2003. PMID: 12751386

4

Mechanisms of tumor vascular shutdown induced by 5,6-dimethylxanthenone-4-acetic acid (DMXAA): Increased tumor vascular permeability.

Zhao L, Ching LM, Kestell P, Kelland LR, Baguley BC. Zhao L, et al. Among authors: kelland lr. Int J Cancer. 2005 Aug 20;116(2):322-6. doi: 10.1002/ijc.21005. Int J Cancer. 2005. PMID: 15800918

5

Preclinical antitumor activity and pharmacodynamic studies with the farnesyl protein transferase inhibitor R115777 in human breast cancer.

Kelland LR, Smith V, Valenti M, Patterson L, Clarke PA, Detre S, End D, Howes AJ, Dowsett M, Workman P, Johnston SR. Kelland LR, et al. Clin Cancer Res. 2001 Nov;7(11):3544-50. Clin Cancer Res. 2001. PMID: 11705875

6

Pharmacokinetic-pharmacodynamic relationships for the heat shock protein 90 molecular chaperone inhibitor 17-allylamino, 17-demethoxygeldanamycin in human ovarian cancer xenograft models.

Banerji U, Walton M, Raynaud F, Grimshaw R, Kelland L, Valenti M, Judson I, Workman P. Banerji U, et al. Clin Cancer Res. 2005 Oct 1;11(19 Pt 1):7023-32. doi: 10.1158/1078-0432.CCR-05-0518. Clin Cancer Res. 2005. PMID: 16203796

7

In vitro and in vivo pharmacokinetic-pharmacodynamic relationships for the trisubstituted aminopurine cyclin-dependent kinase inhibitors olomoucine, bohemine and CYC202.

Raynaud FI, Whittaker SR, Fischer PM, McClue S, Walton MI, Barrie SE, Garrett MD, Rogers P, Clarke SJ, Kelland LR, Valenti M, Brunton L, Eccles S, Lane DP, Workman P. Raynaud FI, et al. Among authors: kelland lr. Clin Cancer Res. 2005 Jul 1;11(13):4875-87. doi: 10.1158/1078-0432.CCR-04-2264. Clin Cancer Res. 2005. PMID: 16000586

8

cis-Amminedichloro(2-methylpyridine) platinum(II) (AMD473), a novel sterically hindered platinum complex: in vivo activity, toxicology, and pharmacokinetics in mice.

Raynaud FI, Boxall FE, Goddard PM, Valenti M, Jones M, Murrer BA, Abrams M, Kelland LR. Raynaud FI, et al. Among authors: kelland lr. Clin Cancer Res. 1997 Nov;3(11):2063-74. Clin Cancer Res. 1997. PMID: 9815598

9

Targeting the limitless replicative potential of cancer: the telomerase/telomere pathway.

Kelland L. Kelland L. Clin Cancer Res. 2007 Sep 1;13(17):4960-3. doi: 10.1158/1078-0432.CCR-07-0422. Clin Cancer Res. 2007. PMID: 17785545 Review.

10

SJG-136 (NSC 694501), a novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity: part 1: cellular pharmacology, in vitro and initial in vivo antitumor activity.

Hartley JA, Spanswick VJ, Brooks N, Clingen PH, McHugh PJ, Hochhauser D, Pedley RB, Kelland LR, Alley MC, Schultz R, Hollingshead MG, Schweikart KM, Tomaszewski JE, Sausville EA, Gregson SJ, Howard PW, Thurston DE. Hartley JA, et al. Among authors: kelland lr. Cancer Res. 2004 Sep 15;64(18):6693-9. doi: 10.1158/0008-5472.CAN-03-2941. Cancer Res. 2004. PMID: 15374986

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