Nelson SD - Search Results

1

Nrf2 activation involves an oxidative-stress independent pathway in tetrafluoroethylcysteine-induced cytotoxicity.

Ho HK, White CC, Fernandez C, Fausto N, Kavanagh TJ, Nelson SD, Bruschi SA. Ho HK, et al. Among authors: nelson sd. Toxicol Sci. 2005 Aug;86(2):354-64. doi: 10.1093/toxsci/kfi205. Epub 2005 May 18. Toxicol Sci. 2005. PMID: 15901913

2

BCL-xL overexpression effectively protects against tetrafluoroethylcysteine-induced intramitochondrial damage and cell death.

Ho HK, Hu ZH, Tzung SP, Hockenbery DM, Fausto N, Nelson SD, Bruschi SA. Ho HK, et al. Among authors: nelson sd. Biochem Pharmacol. 2005 Jan 1;69(1):147-57. doi: 10.1016/j.bcp.2004.08.030. Biochem Pharmacol. 2005. PMID: 15588723

3

Cytosolic heat shock proteins and heme oxygenase-1 are preferentially induced in response to specific and localized intramitochondrial damage by tetrafluoroethylcysteine.

Ho HK, Jia Y, Coe KJ, Gao Q, Doneanu CE, Hu Z, Bammler TK, Beyer RP, Fausto N, Bruschi SA, Nelson SD. Ho HK, et al. Among authors: nelson sd. Biochem Pharmacol. 2006 Jun 28;72(1):80-90. doi: 10.1016/j.bcp.2006.03.019. Epub 2006 Mar 29. Biochem Pharmacol. 2006. PMID: 16678137

4

Mitochondrial aconitase modification, functional inhibition, and evidence for a supramolecular complex of the TCA cycle by the renal toxicant S-(1,1,2,2-tetrafluoroethyl)-L-cysteine.

James EA, Gygi SP, Adams ML, Pierce RH, Fausto N, Aebersold RH, Nelson SD, Bruschi SA. James EA, et al. Among authors: nelson sd. Biochemistry. 2002 May 28;41(21):6789-97. doi: 10.1021/bi020038j. Biochemistry. 2002. PMID: 12022883

5

Comparison of the cytotoxicity of the nitroaromatic drug flutamide to its cyano analogue in the hepatocyte cell line TAMH: evidence for complex I inhibition and mitochondrial dysfunction using toxicogenomic screening.

Coe KJ, Jia Y, Ho HK, Rademacher P, Bammler TK, Beyer RP, Farin FM, Woodke L, Plymate SR, Fausto N, Nelson SD. Coe KJ, et al. Among authors: nelson sd. Chem Res Toxicol. 2007 Sep;20(9):1277-90. doi: 10.1021/tx7001349. Epub 2007 Aug 17. Chem Res Toxicol. 2007. PMID: 17702527 Free PMC article.

6

Proteomic analysis of acetaminophen-induced changes in mitochondrial protein expression using spectral counting.

Stamper BD, Mohar I, Kavanagh TJ, Nelson SD. Stamper BD, et al. Among authors: nelson sd. Chem Res Toxicol. 2011 Apr 18;24(4):549-58. doi: 10.1021/tx1004198. Epub 2011 Feb 18. Chem Res Toxicol. 2011. PMID: 21329376 Free PMC article.

7

Acetaminophen-induced liver damage in mice is associated with gender-specific adduction of peroxiredoxin-6.

Mohar I, Stamper BD, Rademacher PM, White CC, Nelson SD, Kavanagh TJ. Mohar I, et al. Among authors: nelson sd. Redox Biol. 2014 Jan 20;2:377-87. doi: 10.1016/j.redox.2014.01.008. eCollection 2014. Redox Biol. 2014. PMID: 24563856 Free PMC article.

8

Comparative metabonomic analysis of hepatotoxicity induced by acetaminophen and its less toxic meta-isomer.

Kyriakides M, Maitre L, Stamper BD, Mohar I, Kavanagh TJ, Foster J, Wilson ID, Holmes E, Nelson SD, Coen M. Kyriakides M, et al. Among authors: nelson sd. Arch Toxicol. 2016 Dec;90(12):3073-3085. doi: 10.1007/s00204-015-1655-x. Epub 2016 Jan 9. Arch Toxicol. 2016. PMID: 26746206 Free PMC article.

9

Enhanced acetaminophen hepatotoxicity in transgenic mice overexpressing BCL-2.

Adams ML, Pierce RH, Vail ME, White CC, Tonge RP, Kavanagh TJ, Fausto N, Nelson SD, Bruschi SA. Adams ML, et al. Among authors: nelson sd. Mol Pharmacol. 2001 Nov;60(5):907-15. doi: 10.1124/mol.60.5.907. Mol Pharmacol. 2001. PMID: 11641418

10

Role of CYP1A2 in the hepatotoxicity of acetaminophen: investigations using Cyp1a2 null mice.

Tonge RP, Kelly EJ, Bruschi SA, Kalhorn T, Eaton DL, Nebert DW, Nelson SD. Tonge RP, et al. Among authors: nelson sd. Toxicol Appl Pharmacol. 1998 Nov;153(1):102-8. doi: 10.1006/taap.1998.8543. Toxicol Appl Pharmacol. 1998. PMID: 9875304

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