Korsmeyer SJ - Search Results

1

An inhibitor of Bcl-2 family proteins induces regression of solid tumours.

Oltersdorf T, Elmore SW, Shoemaker AR, Armstrong RC, Augeri DJ, Belli BA, Bruncko M, Deckwerth TL, Dinges J, Hajduk PJ, Joseph MK, Kitada S, Korsmeyer SJ, Kunzer AR, Letai A, Li C, Mitten MJ, Nettesheim DG, Ng S, Nimmer PM, O'Connor JM, Oleksijew A, Petros AM, Reed JC, Shen W, Tahir SK, Thompson CB, Tomaselli KJ, Wang B, Wendt MD, Zhang H, Fesik SW, Rosenberg SH. Oltersdorf T, et al. Among authors: korsmeyer sj. Nature. 2005 Jun 2;435(7042):677-81. doi: 10.1038/nature03579. Epub 2005 May 15. Nature. 2005. PMID: 15902208 Free article.

2

Fas-induced activation of the cell death-related protease CPP32 Is inhibited by Bcl-2 and by ICE family protease inhibitors.

Armstrong RC, Aja T, Xiang J, Gaur S, Krebs JF, Hoang K, Bai X, Korsmeyer SJ, Karanewsky DS, Fritz LC, Tomaselli KJ. Armstrong RC, et al. Among authors: korsmeyer sj. J Biol Chem. 1996 Jul 12;271(28):16850-5. doi: 10.1074/jbc.271.28.16850. J Biol Chem. 1996. PMID: 8663439 Free article.

3

Antiapoptotic BCL-2 is required for maintenance of a model leukemia.

Letai A, Sorcinelli MD, Beard C, Korsmeyer SJ. Letai A, et al. Among authors: korsmeyer sj. Cancer Cell. 2004 Sep;6(3):241-9. doi: 10.1016/j.ccr.2004.07.011. Cancer Cell. 2004. PMID: 15380515 Free article.

4

Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members.

Certo M, Del Gaizo Moore V, Nishino M, Wei G, Korsmeyer S, Armstrong SA, Letai A. Certo M, et al. Cancer Cell. 2006 May;9(5):351-65. doi: 10.1016/j.ccr.2006.03.027. Cancer Cell. 2006. PMID: 16697956 Free article.

5

Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.

Opferman JT, Letai A, Beard C, Sorcinelli MD, Ong CC, Korsmeyer SJ. Opferman JT, et al. Among authors: korsmeyer sj. Nature. 2003 Dec 11;426(6967):671-6. doi: 10.1038/nature02067. Nature. 2003. PMID: 14668867 Free article.

6

Suppression of developmental retinal cell death but not of photoreceptor degeneration in Bax-deficient mice.

Mosinger Ogilvie J, Deckwerth TL, Knudson CM, Korsmeyer SJ. Mosinger Ogilvie J, et al. Among authors: korsmeyer sj. Invest Ophthalmol Vis Sci. 1998 Aug;39(9):1713-20. Invest Ophthalmol Vis Sci. 1998. PMID: 9699561

7

Multiple Bcl-2 family members demonstrate selective dimerizations with Bax.

Sedlak TW, Oltvai ZN, Yang E, Wang K, Boise LH, Thompson CB, Korsmeyer SJ. Sedlak TW, et al. Among authors: korsmeyer sj. Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7834-8. doi: 10.1073/pnas.92.17.7834. Proc Natl Acad Sci U S A. 1995. PMID: 7644501 Free PMC article.

8

Placement of the BCL2 family member BAX in the death pathway of sympathetic neurons activated by trophic factor deprivation.

Deckwerth TL, Easton RM, Knudson CM, Korsmeyer SJ, Johnson EM Jr. Deckwerth TL, et al. Among authors: korsmeyer sj. Exp Neurol. 1998 Jul;152(1):150-62. doi: 10.1006/exnr.1998.6846. Exp Neurol. 1998. PMID: 9682022

9

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics.

Letai A, Bassik MC, Walensky LD, Sorcinelli MD, Weiler S, Korsmeyer SJ. Letai A, et al. Among authors: korsmeyer sj. Cancer Cell. 2002 Sep;2(3):183-92. doi: 10.1016/s1535-6108(02)00127-7. Cancer Cell. 2002. PMID: 12242151 Free article.

10

Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.

Kandasamy K, Srinivasula SM, Alnemri ES, Thompson CB, Korsmeyer SJ, Bryant JL, Srivastava RK. Kandasamy K, et al. Among authors: korsmeyer sj. Cancer Res. 2003 Apr 1;63(7):1712-21. Cancer Res. 2003. PMID: 12670926

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