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Lack of responsiveness to TGF-beta1 in a thyroid carcinoma cell line with functional type I and type II TGF-beta receptors and Smad proteins, suggests a novel mechanism for TGF-beta insensitivity in carcinoma cells.
Heldin NE, Bergström D, Hermansson A, Bergenstråhle A, Nakao A, Westermark B, ten Dijke P. Heldin NE, et al. Among authors: bergenstrahle a. Mol Cell Endocrinol. 1999 Jul 20;153(1-2):79-90. doi: 10.1016/s0303-7207(99)00086-6. Mol Cell Endocrinol. 1999. PMID: 10459856