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Page 1
Discovery and development of dimeric podocarpic acid leads as potent agonists of liver X receptor with HDL cholesterol raising activity in mice and hamsters.
Singh SB, Ondeyka JG, Liu W, Chen S, Chen TS, Li X, Bouffard A, Dropinski J, Jones AB, McCormick S, Hayes N, Wang J, Sharma N, Macnaul K, Hernandez M, Chao YS, Baffic J, Lam MH, Burton C, Sparrow CP, Menke JG. Singh SB, et al. Among authors: lam mh. Bioorg Med Chem Lett. 2005 Jun 2;15(11):2824-8. doi: 10.1016/j.bmcl.2005.03.100. Bioorg Med Chem Lett. 2005. PMID: 15911262
A potent synthetic LXR agonist is more effective than cholesterol loading at inducing ABCA1 mRNA and stimulating cholesterol efflux.
Sparrow CP, Baffic J, Lam MH, Lund EG, Adams AD, Fu X, Hayes N, Jones AB, Macnaul KL, Ondeyka J, Singh S, Wang J, Zhou G, Moller DE, Wright SD, Menke JG. Sparrow CP, et al. Among authors: lam mh. J Biol Chem. 2002 Mar 22;277(12):10021-7. doi: 10.1074/jbc.M108225200. Epub 2002 Jan 14. J Biol Chem. 2002. PMID: 11790770 Free article.
A novel peroxisome proliferator-activated receptor alpha/gamma dual agonist demonstrates favorable effects on lipid homeostasis.
Guo Q, Sahoo SP, Wang PR, Milot DP, Ippolito MC, Wu MS, Baffic J, Biswas C, Hernandez M, Lam MH, Sharma N, Han W, Kelly LJ, MacNaul KL, Zhou G, Desai R, Heck JV, Doebber TW, Berger JP, Moller DE, Sparrow CP, Chao YS, Wright SD. Guo Q, et al. Among authors: lam mh. Endocrinology. 2004 Apr;145(4):1640-8. doi: 10.1210/en.2003-1270. Epub 2003 Dec 30. Endocrinology. 2004. PMID: 14701675
Fluorogenic substrates for high-throughput measurements of endothelial lipase activity.
Mitnaul LJ, Tian J, Burton C, Lam MH, Zhu Y, Olson SH, Schneeweis JE, Zuck P, Pandit S, Anderson M, Maletic MM, Waddell ST, Wright SD, Sparrow CP, Lund EG. Mitnaul LJ, et al. Among authors: lam mh. J Lipid Res. 2007 Feb;48(2):472-82. doi: 10.1194/jlr.D600041-JLR200. Epub 2006 Nov 7. J Lipid Res. 2007. PMID: 17090660 Free article.
Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis.
Davis HR Jr, Zhu LJ, Hoos LM, Tetzloff G, Maguire M, Liu J, Yao X, Iyer SP, Lam MH, Lund EG, Detmers PA, Graziano MP, Altmann SW. Davis HR Jr, et al. Among authors: lam mh. J Biol Chem. 2004 Aug 6;279(32):33586-92. doi: 10.1074/jbc.M405817200. Epub 2004 Jun 1. J Biol Chem. 2004. PMID: 15173162 Free article.
Proteome-scale discovery of protein degradation and stabilization effectors.
Poirson J, Cho H, Dhillon A, Haider S, Imrit AZ, Lam MHY, Alerasool N, Lacoste J, Mizan L, Wong C, Gingras AC, Schramek D, Taipale M. Poirson J, et al. Among authors: lam mhy. Nature. 2024 Apr;628(8009):878-886. doi: 10.1038/s41586-024-07224-3. Epub 2024 Mar 20. Nature. 2024. PMID: 38509365
Addressing the risk and management of cardiometabolic complications in prostate cancer patients on androgen deprivation therapy and androgen receptor axis-targeted therapy: consensus statements from the Hong Kong Urological Association and the Hong Kong Society of Uro-Oncology.
Poon DMC, Tan GM, Chan K, Chan MTY, Chan TW, Kan RWM, Lam MHC, Leung CLH, Wong KCW, Kam KKH, Ng CF, Chiu PKF. Poon DMC, et al. Among authors: lam mhc. Front Oncol. 2024 Jan 31;14:1345322. doi: 10.3389/fonc.2024.1345322. eCollection 2024. Front Oncol. 2024. PMID: 38357197 Free PMC article. Review.
A territory-wide real-world efficacy and toxicity analysis of abiraterone acetate versus docetaxel in 574 Asian patients with metastatic hormone-sensitive prostate cancer.
Lam BHW, Tsang VHM, Lee MP, Chan K, Liu TC, Ng BYH, Wo BBW, Leung KC, Mui WH, Chan TW, Lam MHC, Siu SWK, Poon DMC. Lam BHW, et al. Among authors: lam mhc. Clin Genitourin Cancer. 2024 Feb;22(1):e75-e85.e1. doi: 10.1016/j.clgc.2023.07.012. Epub 2023 Aug 2. Clin Genitourin Cancer. 2024. PMID: 37604745 Free article.
270 results