Gresh N - Search Results

1

Design, synthesis, and biological evaluation of novel naphthoquinone derivatives with CDC25 phosphatase inhibitory activity.

Brun MP, Braud E, Angotti D, Mondésert O, Quaranta M, Montes M, Miteva M, Gresh N, Ducommun B, Garbay C. Brun MP, et al. Among authors: gresh n. Bioorg Med Chem. 2005 Aug 15;13(16):4871-9. doi: 10.1016/j.bmc.2005.05.005. Bioorg Med Chem. 2005. PMID: 15921913

2

Synthesis and structure-activity relationship of non-peptidic antagonists of neuropilin-1 receptor.

Liu WQ, Megale V, Borriello L, Leforban B, Montès M, Goldwaser E, Gresh N, Piquemal JP, Hadj-Slimane R, Hermine O, Garbay C, Raynaud F, Lepelletier Y, Demange L. Liu WQ, et al. Among authors: gresh n. Bioorg Med Chem Lett. 2014 Sep 1;24(17):4254-9. doi: 10.1016/j.bmcl.2014.07.028. Epub 2014 Jul 17. Bioorg Med Chem Lett. 2014. PMID: 25091928

3

Novel 1,4-benzodiazepine derivatives with antiproliferative properties on tumor cell lines.

Dourlat J, Liu WQ, Gresh N, Garbay C. Dourlat J, et al. Among authors: gresh n. Bioorg Med Chem Lett. 2007 May 1;17(9):2527-30. doi: 10.1016/j.bmcl.2007.02.016. Epub 2007 Feb 9. Bioorg Med Chem Lett. 2007. PMID: 17317183 Free article.

4

Novel naphthoquinone and quinolinedione inhibitors of CDC25 phosphatase activity with antiproliferative properties.

Braud E, Goddard ML, Kolb S, Brun MP, Mondésert O, Quaranta M, Gresh N, Ducommun B, Garbay C. Braud E, et al. Among authors: gresh n. Bioorg Med Chem. 2008 Oct 1;16(19):9040-9. doi: 10.1016/j.bmc.2008.08.009. Epub 2008 Aug 7. Bioorg Med Chem. 2008. PMID: 18789703

5

Small peptides containing phosphotyrosine and adjacent alphaMe-phosphotyrosine or its mimetics as highly potent inhibitors of Grb2 SH2 domain.

Liu WQ, Vidal M, Gresh N, Roques BP, Garbay C. Liu WQ, et al. Among authors: gresh n. J Med Chem. 1999 Sep 9;42(18):3737-41. doi: 10.1021/jm9911074. J Med Chem. 1999. PMID: 10479306

6

Synthesis of aryl phosphates based on pyrimidine and triazine scaffolds.

Courme C, Gresh N, Vidal M, Lenoir C, Garbay C, Florent JC, Bertounesque E. Courme C, et al. Among authors: gresh n. Eur J Med Chem. 2010 Jan;45(1):244-55. doi: 10.1016/j.ejmech.2009.10.003. Epub 2009 Oct 9. Eur J Med Chem. 2010. PMID: 19906464

7

Design of peptoid analogue dimers and measure of their affinity for Grb2 SH3 domains.

Vidal M, Liu WQ, Lenoir C, Salzmann J, Gresh N, Garbay C. Vidal M, et al. Among authors: gresh n. Biochemistry. 2004 Jun 15;43(23):7336-44. doi: 10.1021/bi030252n. Biochemistry. 2004. PMID: 15182177

8

Polarizable water molecules in ligand-macromolecule recognition. Impact on the relative affinities of competing pyrrolopyrimidine inhibitors for FAK kinase.

de Courcy B, Piquemal JP, Garbay C, Gresh N. de Courcy B, et al. Among authors: gresh n. J Am Chem Soc. 2010 Mar 17;132(10):3312-20. doi: 10.1021/ja9059156. J Am Chem Soc. 2010. PMID: 20178314

9

Potent inhibitors of CDK5 derived from roscovitine: synthesis, biological evaluation and molecular modelling.

Demange L, Abdellah FN, Lozach O, Ferandin Y, Gresh N, Meijer L, Galons H. Demange L, et al. Among authors: gresh n. Bioorg Med Chem Lett. 2013 Jan 1;23(1):125-31. doi: 10.1016/j.bmcl.2012.10.141. Epub 2012 Nov 10. Bioorg Med Chem Lett. 2013. PMID: 23218601

10

Conformational analysis of a polyconjugated protein-binding ligand by joint quantum chemistry and polarizable molecular mechanics. Addressing the issues of anisotropy, conjugation, polarization, and multipole transferability.

Goldwaser E, de Courcy B, Demange L, Garbay C, Raynaud F, Hadj-Slimane R, Piquemal JP, Gresh N. Goldwaser E, et al. Among authors: gresh n. J Mol Model. 2014 Nov;20(11):2472. doi: 10.1007/s00894-014-2472-5. Epub 2014 Nov 1. J Mol Model. 2014. PMID: 25367040

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