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5-Aryl thiazolidine-2,4-diones as selective PPARgamma agonists.
Koyama H, Boueres JK, Han W, Metzger EJ, Bergman JP, Gratale DF, Miller DJ, Tolman RL, MacNaul KL, Berger JP, Doebber TW, Leung K, Moller DE, Heck JV, Sahoo SP. Koyama H, et al. Bioorg Med Chem Lett. 2003 May 19;13(10):1801-4. doi: 10.1016/s0960-894x(03)00257-9. Bioorg Med Chem Lett. 2003. PMID: 12729668
(2R)-2-ethylchromane-2-carboxylic acids: discovery of novel PPARalpha/gamma dual agonists as antihyperglycemic and hypolipidemic agents.
Koyama H, Miller DJ, Boueres JK, Desai RC, Jones AB, Berger JP, MacNaul KL, Kelly LJ, Doebber TW, Wu MS, Zhou G, Wang PR, Ippolito MC, Chao YS, Agrawal AK, Franklin R, Heck JV, Wright SD, Moller DE, Sahoo SP. Koyama H, et al. J Med Chem. 2004 Jun 3;47(12):3255-63. doi: 10.1021/jm030621d. J Med Chem. 2004. PMID: 15163205
Deep generative abnormal lesion emphasization validated by nine radiologists and 1000 chest X-rays with lung nodules.
Hanaoka S, Nomura Y, Hayashi N, Sato I, Miki S, Yoshikawa T, Shibata H, Nakao T, Takenaga T, Koyama H, Cho S, Kanemaru N, Fujimoto K, Sakamoto N, Nishiyama T, Matsuzaki H, Yamamichi N, Abe O. Hanaoka S, et al. Among authors: koyama h. PLoS One. 2024 Dec 12;19(12):e0315646. doi: 10.1371/journal.pone.0315646. eCollection 2024. PLoS One. 2024. PMID: 39666722 Free PMC article.
1,822 results