Murrills RJ - Search Results

1

Isogenic human cell lines for drug discovery: regulation of target gene expression by engineered zinc-finger protein transcription factors.

Liu PQ, Tan S, Mendel MC, Murrills RJ, Bhat BM, Schlag B, Samuel R, Matteo JJ, de la Rosa R, Howes K, Reik A, Case CC, Bex FJ, Young K, Gregory PD. Liu PQ, et al. Among authors: murrills rj. J Biomol Screen. 2005 Jun;10(4):304-13. doi: 10.1177/1087057104272663. J Biomol Screen. 2005. PMID: 15964931

2

In vitro and in vivo activities of C-terminally truncated PTH peptides reveal a disconnect between cAMP signaling and functional activity.

Murrills RJ, Matteo JJ, Samuel RL, Andrews JL, Bhat BM, Coleburn VE, Kharode YP, Bex FJ. Murrills RJ, et al. Bone. 2004 Dec;35(6):1263-72. doi: 10.1016/j.bone.2004.08.015. Bone. 2004. PMID: 15589208

3

Parathyroid hormone synergizes with non-cyclic AMP pathways to activate the cyclic AMP response element.

Murrills RJ, Andrews JL, Samuel RL, Coleburn VE, Bhat BM, Bhat RA, Bex FJ, Bodine PV. Murrills RJ, et al. J Cell Biochem. 2009 Apr 1;106(5):887-95. doi: 10.1002/jcb.22057. J Cell Biochem. 2009. PMID: 19180574

4

A cell-based Dkk1 binding assay reveals roles for extracellular domains of LRP5 in Dkk1 interaction and highlights differences between wild-type and the high bone mass mutant LRP5(G171V).

Murrills RJ, Matteo JJ, Bhat BM, Coleburn VE, Allen KM, Chen W, Damagnez V, Bhat RA, Bex FJ, Bodine PV. Murrills RJ, et al. J Cell Biochem. 2009 Dec 1;108(5):1066-75. doi: 10.1002/jcb.22335. J Cell Biochem. 2009. PMID: 19746449

5

(1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methanamine: a wingless beta-catenin agonist that increases bone formation rate.

Pelletier JC, Lundquist JT 4th, Gilbert AM, Alon N, Bex FJ, Bhat BM, Bursavich MG, Coleburn VE, Felix LA, Green DM, Green P, Hauze DB, Kharode YP, Lam HS, Lockhead SR, Magolda RL, Matteo JJ, Mehlmann JF, Milligan C, Murrills RJ, Pirrello J, Selim S, Sharp MC, Unwalla RJ, Vera MD, Wrobel JE, Yaworsky P, Bodine PV. Pelletier JC, et al. Among authors: murrills rj. J Med Chem. 2009 Nov 26;52(22):6962-5. doi: 10.1021/jm9014197. J Med Chem. 2009. PMID: 19856966

6

Hit to lead studies on (hetero)arylpyrimidines--agonists of the canonical Wnt-beta-catenin cellular messaging system.

Gilbert AM, Bursavich MG, Alon N, Bhat BM, Bex FJ, Cain M, Coleburn V, Gironda V, Green P, Hauze DB, Kharode Y, Krishnamurthy G, Kirisits M, Lam HS, Liu YB, Lombardi S, Matteo J, Murrills R, Robinson JA, Selim S, Sharp M, Unwalla R, Varadarajan U, Zhao W, Yaworsky PJ. Gilbert AM, et al. Bioorg Med Chem Lett. 2010 Jan 1;20(1):366-70. doi: 10.1016/j.bmcl.2009.10.093. Epub 2009 Oct 25. Bioorg Med Chem Lett. 2010. PMID: 19897365

7

Osteogenic effects of a potent Src-over-Abl-selective kinase inhibitor in the mouse.

Murrills RJ, Fukayama S, Boschelli F, Matteo JJ, Owens J, Golas JM, Patel D, Lane G, Liu YB, Carter L, Jussif J, Spaulding V, Wang YD, Boschelli DH, McKew JC, Li XJ, Lockhead S, Milligan C, Kharode YP, Diesl V, Bai Y, Follettie M, Bex FJ, Komm B, Bodine PV. Murrills RJ, et al. J Pharmacol Exp Ther. 2012 Mar;340(3):676-87. doi: 10.1124/jpet.111.185793. Epub 2011 Dec 9. J Pharmacol Exp Ther. 2012. PMID: 22171089

8

Identification of a PTH regulated gene selectively induced in vivo during PTH-mediated bone formation.

Robinson JA, Susulic V, Liu YB, Taylor C, Hardenburg J, Gironda V, Zhao W, Kharode Y, McLarney S, Bai Y, Malone DP, Murrills R, Bex F. Robinson JA, et al. J Cell Biochem. 2006 Aug 1;98(5):1203-20. doi: 10.1002/jcb.20822. J Cell Biochem. 2006. PMID: 16514668

9

PTH-dependent adenylyl cyclase activation in SaOS-2 cells: passage dependent effects on G protein interactions.

Gao H, Bodine PV, Murrills R, Bex FJ, Bilezikian JP, Morris SA. Gao H, et al. J Cell Physiol. 2002 Oct;193(1):10-8. doi: 10.1002/jcp.10141. J Cell Physiol. 2002. PMID: 12209875

10

Expression of meltrin-alpha mRNA is not restricted to fusagenic cells.

Harris HA, Murrills RJ, Komm BS. Harris HA, et al. Among authors: murrills rj. J Cell Biochem. 1997 Oct 1;67(1):136-42. doi: 10.1002/(sici)1097-4644(19971001)67:1<136::aid-jcb14>3.0.co;2-f. J Cell Biochem. 1997. PMID: 9328847

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