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An integrative genomics approach to infer causal associations between gene expression and disease.
Schadt EE, Lamb J, Yang X, Zhu J, Edwards S, Guhathakurta D, Sieberts SK, Monks S, Reitman M, Zhang C, Lum PY, Leonardson A, Thieringer R, Metzger JM, Yang L, Castle J, Zhu H, Kash SF, Drake TA, Sachs A, Lusis AJ. Schadt EE, et al. Among authors: guhathakurta d. Nat Genet. 2005 Jul;37(7):710-7. doi: 10.1038/ng1589. Epub 2005 Jun 19. Nat Genet. 2005. PMID: 15965475 Free PMC article.
Mapping the genetic architecture of gene expression in human liver.
Schadt EE, Molony C, Chudin E, Hao K, Yang X, Lum PY, Kasarskis A, Zhang B, Wang S, Suver C, Zhu J, Millstein J, Sieberts S, Lamb J, GuhaThakurta D, Derry J, Storey JD, Avila-Campillo I, Kruger MJ, Johnson JM, Rohl CA, van Nas A, Mehrabian M, Drake TA, Lusis AJ, Smith RC, Guengerich FP, Strom SC, Schuetz E, Rushmore TH, Ulrich R. Schadt EE, et al. Among authors: guhathakurta d. PLoS Biol. 2008 May 6;6(5):e107. doi: 10.1371/journal.pbio.0060107. PLoS Biol. 2008. PMID: 18462017 Free PMC article.
A comprehensive transcript index of the human genome generated using microarrays and computational approaches.
Schadt EE, Edwards SW, GuhaThakurta D, Holder D, Ying L, Svetnik V, Leonardson A, Hart KW, Russell A, Li G, Cavet G, Castle J, McDonagh P, Kan Z, Chen R, Kasarskis A, Margarint M, Caceres RM, Johnson JM, Armour CD, Garrett-Engele PW, Tsinoremas NF, Shoemaker DD. Schadt EE, et al. Among authors: guhathakurta d. Genome Biol. 2004;5(10):R73. doi: 10.1186/gb-2004-5-10-r73. Epub 2004 Sep 23. Genome Biol. 2004. PMID: 15461792 Free PMC article.
Identification of genes and networks driving cardiovascular and metabolic phenotypes in a mouse F2 intercross.
Derry JM, Zhong H, Molony C, MacNeil D, Guhathakurta D, Zhang B, Mudgett J, Small K, El Fertak L, Guimond A, Selloum M, Zhao W, Champy MF, Monassier L, Vogt T, Cully D, Kasarskis A, Schadt EE. Derry JM, et al. Among authors: guhathakurta d. PLoS One. 2010 Dec 14;5(12):e14319. doi: 10.1371/journal.pone.0014319. PLoS One. 2010. PMID: 21179467 Free PMC article.
35 results