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447 results

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Page 1
Studies on the apoptotic activity of natural and synthetic retinoids: discovery of a new class of synthetic terphenyls that potently support cell growth and inhibit apoptosis in neuronal and HL-60 cells.
Simoni D, Giannini G, Roberti M, Rondanin R, Baruchello R, Rossi M, Grisolia G, Invidiata FP, Aiello S, Marino S, Cavallini S, Siniscalchi A, Gebbia N, Crosta L, Grimaudo S, Abbadessa V, Di Cristina A, Tolomeo M. Simoni D, et al. Among authors: giannini g. J Med Chem. 2005 Jun 30;48(13):4293-9. doi: 10.1021/jm049080y. J Med Chem. 2005. PMID: 15974583
Novel 3,4-isoxazolediamides as potent inhibitors of chaperone heat shock protein 90.
Baruchello R, Simoni D, Grisolia G, Barbato G, Marchetti P, Rondanin R, Mangiola S, Giannini G, Brunetti T, Alloatti D, Gallo G, Ciacci A, Vesci L, Castorina M, Milazzo FM, Cervoni ML, Guglielmi MB, Barbarino M, Foderà R, Pisano C, Cabri W. Baruchello R, et al. Among authors: giannini g. J Med Chem. 2011 Dec 22;54(24):8592-604. doi: 10.1021/jm201155e. Epub 2011 Nov 23. J Med Chem. 2011. PMID: 22066525
4,5,6,7-Tetrahydro-isoxazolo-[4,5-c]-pyridines as a new class of cytotoxic Hsp90 inhibitors.
Baruchello R, Simoni D, Marchetti P, Rondanin R, Mangiola S, Costantini C, Meli M, Giannini G, Vesci L, Carollo V, Brunetti T, Battistuzzi G, Tolomeo M, Cabri W. Baruchello R, et al. Among authors: giannini g. Eur J Med Chem. 2014 Apr 9;76:53-60. doi: 10.1016/j.ejmech.2014.01.056. Epub 2014 Jan 30. Eur J Med Chem. 2014. PMID: 24565573
Heterocyclic and phenyl double-bond-locked combretastatin analogues possessing potent apoptosis-inducing activity in HL60 and in MDR cell lines.
Simoni D, Grisolia G, Giannini G, Roberti M, Rondanin R, Piccagli L, Baruchello R, Rossi M, Romagnoli R, Invidiata FP, Grimaudo S, Jung MK, Hamel E, Gebbia N, Crosta L, Abbadessa V, Di Cristina A, Dusonchet L, Meli M, Tolomeo M. Simoni D, et al. Among authors: giannini g. J Med Chem. 2005 Feb 10;48(3):723-36. doi: 10.1021/jm049622b. J Med Chem. 2005. PMID: 15689156
Novel combretastatin analogues endowed with antitumor activity.
Simoni D, Romagnoli R, Baruchello R, Rondanin R, Rizzi M, Pavani MG, Alloatti D, Giannini G, Marcellini M, Riccioni T, Castorina M, Guglielmi MB, Bucci F, Carminati P, Pisano C. Simoni D, et al. Among authors: giannini g. J Med Chem. 2006 Jun 1;49(11):3143-52. doi: 10.1021/jm0510732. J Med Chem. 2006. PMID: 16722633
Synthesis and structure-activity relationships of a new series of retinoid-related biphenyl-4-ylacrylic acids endowed with antiproliferative and proapoptotic activity.
Cincinelli R, Dallavalle S, Nannei R, Carella S, De Zani D, Merlini L, Penco S, Garattini E, Giannini G, Pisano C, Vesci L, Carminati P, Zuco V, Zanchi C, Zunino F. Cincinelli R, et al. Among authors: giannini g. J Med Chem. 2005 Jul 28;48(15):4931-46. doi: 10.1021/jm049440h. J Med Chem. 2005. PMID: 16033272
Synthesis and cytotoxic activity of polyamine analogues of camptothecin.
Dallavalle S, Giannini G, Alloatti D, Casati A, Marastoni E, Musso L, Merlini L, Morini G, Penco S, Pisano C, Tinelli S, De Cesare M, Beretta GL, Zunino F. Dallavalle S, et al. Among authors: giannini g. J Med Chem. 2006 Aug 24;49(17):5177-86. doi: 10.1021/jm060285b. J Med Chem. 2006. PMID: 16913706
447 results