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Type III-B CRISPR-Cas cascade of proteolytic cleavages.
Steens JA, Bravo JPK, Salazar CRP, Yildiz C, Amieiro AM, Köstlbacher S, Prinsen SHP, Andres AS, Patinios C, Bardis A, Barendregt A, Scheltema RA, Ettema TJG, van der Oost J, Taylor DW, Staals RHJ. Steens JA, et al. Among authors: van der oost j. Science. 2024 Feb 2;383(6682):512-519. doi: 10.1126/science.adk0378. Epub 2024 Feb 1. Science. 2024. PMID: 38301007
Mechanistic and evolutionary insights into a type V-M CRISPR-Cas effector enzyme.
Omura SN, Nakagawa R, Südfeld C, Villegas Warren R, Wu WY, Hirano H, Laffeber C, Kusakizako T, Kise Y, Lebbink JHG, Itoh Y, van der Oost J, Nureki O. Omura SN, et al. Among authors: van der oost j. Nat Struct Mol Biol. 2023 Aug;30(8):1172-1182. doi: 10.1038/s41594-023-01042-3. Epub 2023 Jul 17. Nat Struct Mol Biol. 2023. PMID: 37460897 Free PMC article.
Efficient Genome and Base Editing in Human Cells Using ThermoCas9.
Trasanidou D, Barendse P, Bouzetos E, de Haan L, Bouwmeester H, Staals RHJ, Mougiakos I, van der Oost J. Trasanidou D, et al. Among authors: van der oost j. CRISPR J. 2023 Jun;6(3):278-288. doi: 10.1089/crispr.2023.0005. Epub 2023 May 3. CRISPR J. 2023. PMID: 37134217
Cryo-EM structure of the transposon-associated TnpB enzyme.
Nakagawa R, Hirano H, Omura SN, Nety S, Kannan S, Altae-Tran H, Yao X, Sakaguchi Y, Ohira T, Wu WY, Nakayama H, Shuto Y, Tanaka T, Sano FK, Kusakizako T, Kise Y, Itoh Y, Dohmae N, van der Oost J, Suzuki T, Zhang F, Nureki O. Nakagawa R, et al. Among authors: van der oost j. Nature. 2023 Apr;616(7956):390-397. doi: 10.1038/s41586-023-05933-9. Epub 2023 Apr 5. Nature. 2023. PMID: 37020030 Free PMC article.
The genome editing revolution.
van der Oost J, Patinios C. van der Oost J, et al. Trends Biotechnol. 2023 Mar;41(3):396-409. doi: 10.1016/j.tibtech.2022.12.022. Epub 2023 Jan 27. Trends Biotechnol. 2023. PMID: 36709094 Free article. Review.
342 results