Hermann TW - Search Results

1

The retinoid X receptor agonist bexarotene (Targretin) synergistically enhances the growth inhibitory activity of cytotoxic drugs in non-small cell lung cancer cells.

Hermann TW, Yen WC, Tooker P, Fan B, Roegner K, Negro-Vilar A, Lamph WW, Bissonnette RP. Hermann TW, et al. Lung Cancer. 2005 Oct;50(1):9-18. doi: 10.1016/j.lungcan.2005.05.008. Lung Cancer. 2005. PMID: 15993980

2

Bexarotene (LGD1069, Targretin), a selective retinoid X receptor agonist, prevents and reverses gemcitabine resistance in NSCLC cells by modulating gene amplification.

Tooker P, Yen WC, Ng SC, Negro-Vilar A, Hermann TW. Tooker P, et al. Among authors: hermann tw. Cancer Res. 2007 May 1;67(9):4425-33. doi: 10.1158/0008-5472.CAN-06-4495. Cancer Res. 2007. PMID: 17483357

3

Identification of polymorphisms associated with hypertriglyceridemia and prolonged survival induced by bexarotene in treating non-small cell lung cancer.

Luo W, Schork NJ, Marschke KB, Ng SC, Hermann TW, Zhang J, Sanders JM, Tooker P, Malo N, Zapala MA, Dziewanowska ZE, Negro-Vilar A, Meglasson MD. Luo W, et al. Among authors: hermann tw. Anticancer Res. 2011 Jun;31(6):2303-11. Anticancer Res. 2011. PMID: 21737656

4

Induction of adipocyte-specific gene expression is correlated with mammary tumor regression by the retinoid X receptor-ligand LGD1069 (targretin).

Agarwal VR, Bischoff ED, Hermann T, Lamph WW. Agarwal VR, et al. Cancer Res. 2000 Nov 1;60(21):6033-8. Cancer Res. 2000. PMID: 11085524

5

A proof-of-principle clinical trial of bexarotene in patients with non-small cell lung cancer.

Dragnev KH, Petty WJ, Shah SJ, Lewis LD, Black CC, Memoli V, Nugent WC, Hermann T, Negro-Vilar A, Rigas JR, Dmitrovsky E. Dragnev KH, et al. Clin Cancer Res. 2007 Mar 15;13(6):1794-800. doi: 10.1158/1078-0432.CCR-06-1836. Clin Cancer Res. 2007. PMID: 17363535 Clinical Trial.

6

Structure-guided discovery of novel aminoglycoside mimetics as antibacterial translation inhibitors.

Zhou Y, Gregor VE, Sun Z, Ayida BK, Winters GC, Murphy D, Simonsen KB, Vourloumis D, Fish S, Froelich JM, Wall D, Hermann T. Zhou Y, et al. Antimicrob Agents Chemother. 2005 Dec;49(12):4942-9. doi: 10.1128/AAC.49.12.4942-4949.2005. Antimicrob Agents Chemother. 2005. PMID: 16304156 Free PMC article.

7

Drugs targeting the ribosome.

Hermann T. Hermann T. Curr Opin Struct Biol. 2005 Jun;15(3):355-66. doi: 10.1016/j.sbi.2005.05.001. Curr Opin Struct Biol. 2005. PMID: 15919197 Review.

8

Synthesis of dehydroalanine fragments as thiostrepton side chain mimetics.

Ayida BK, Simonsen KB, Vourloumis D, Hermann T. Ayida BK, et al. Bioorg Med Chem Lett. 2005 May 16;15(10):2457-60. doi: 10.1016/j.bmcl.2005.03.084. Bioorg Med Chem Lett. 2005. PMID: 15863296

9

The adipocyte specific transcription factor C/EBPalpha modulates human ob gene expression.

Miller SG, De Vos P, Guerre-Millo M, Wong K, Hermann T, Staels B, Briggs MR, Auwerx J. Miller SG, et al. Proc Natl Acad Sci U S A. 1996 May 28;93(11):5507-11. doi: 10.1073/pnas.93.11.5507. Proc Natl Acad Sci U S A. 1996. PMID: 8643605 Free PMC article.

10

Formation of retinoid X receptor homodimers leads to repression of T3 response: hormonal cross talk by ligand-induced squelching.

Lehmann JM, Zhang XK, Graupner G, Lee MO, Hermann T, Hoffmann B, Pfahl M. Lehmann JM, et al. Mol Cell Biol. 1993 Dec;13(12):7698-707. doi: 10.1128/mcb.13.12.7698-7707.1993. Mol Cell Biol. 1993. PMID: 8246986 Free PMC article.

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