Yen WC - Search Results

1

The retinoid X receptor agonist bexarotene (Targretin) synergistically enhances the growth inhibitory activity of cytotoxic drugs in non-small cell lung cancer cells.

Hermann TW, Yen WC, Tooker P, Fan B, Roegner K, Negro-Vilar A, Lamph WW, Bissonnette RP. Hermann TW, et al. Among authors: yen wc. Lung Cancer. 2005 Oct;50(1):9-18. doi: 10.1016/j.lungcan.2005.05.008. Lung Cancer. 2005. PMID: 15993980

2

Synergistic effect of a retinoid X receptor-selective ligand bexarotene (LGD1069, Targretin) and paclitaxel (Taxol) in mammary carcinoma.

Yen WC, Prudente RY, Lamph WW. Yen WC, et al. Breast Cancer Res Treat. 2004 Nov;88(2):141-8. doi: 10.1007/s10549-004-1426-5. Breast Cancer Res Treat. 2004. PMID: 15564797

3

A selective retinoid X receptor agonist bexarotene (Targretin) prevents and overcomes acquired paclitaxel (Taxol) resistance in human non-small cell lung cancer.

Yen WC, Corpuz MR, Prudente RY, Cooke TA, Bissonnette RP, Negro-Vilar A, Lamph WW. Yen WC, et al. Clin Cancer Res. 2004 Dec 15;10(24):8656-64. doi: 10.1158/1078-0432.CCR-04-0979. Clin Cancer Res. 2004. PMID: 15623650

4

The selective retinoid X receptor agonist bexarotene (LGD1069, Targretin) prevents and overcomes multidrug resistance in advanced breast carcinoma.

Yen WC, Lamph WW. Yen WC, et al. Mol Cancer Ther. 2005 May;4(5):824-34. doi: 10.1158/1535-7163.MCT-05-0018. Mol Cancer Ther. 2005. PMID: 15897247

5

A selective retinoid X receptor agonist bexarotene (LGD1069, Targretin) prevents and overcomes multidrug resistance in advanced prostate cancer.

Yen WC, Lamph WW. Yen WC, et al. Prostate. 2006 Feb 15;66(3):305-16. doi: 10.1002/pros.20347. Prostate. 2006. PMID: 16245282

6

Differentiation and growth inhibition mediated via the RXR:PPARgamma heterodimer in colon cancer.

Cesario RM, Stone J, Yen WC, Bissonnette RP, Lamph WW. Cesario RM, et al. Among authors: yen wc. Cancer Lett. 2006 Aug 28;240(2):225-33. doi: 10.1016/j.canlet.2005.09.010. Epub 2005 Nov 3. Cancer Lett. 2006. PMID: 16271436

7

Bexarotene (LGD1069, Targretin), a selective retinoid X receptor agonist, prevents and reverses gemcitabine resistance in NSCLC cells by modulating gene amplification.

Tooker P, Yen WC, Ng SC, Negro-Vilar A, Hermann TW. Tooker P, et al. Among authors: yen wc. Cancer Res. 2007 May 1;67(9):4425-33. doi: 10.1158/0008-5472.CAN-06-4495. Cancer Res. 2007. PMID: 17483357

8

LGD-5552, an antiinflammatory glucocorticoid receptor ligand with reduced side effects, in vivo.

López FJ, Ardecky RJ, Bebo B, Benbatoul K, De Grandpre L, Liu S, Leibowitz MD, Marschke K, Rosen J, Rungta D, Viveros HO, Yen WC, Zhi L, Negro-Vilar A, Miner JN. López FJ, et al. Among authors: yen wc. Endocrinology. 2008 May;149(5):2080-9. doi: 10.1210/en.2007-1353. Epub 2008 Jan 24. Endocrinology. 2008. PMID: 18218700

9

DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency.

Hoey T, Yen WC, Axelrod F, Basi J, Donigian L, Dylla S, Fitch-Bruhns M, Lazetic S, Park IK, Sato A, Satyal S, Wang X, Clarke MF, Lewicki J, Gurney A. Hoey T, et al. Among authors: yen wc. Cell Stem Cell. 2009 Aug 7;5(2):168-77. doi: 10.1016/j.stem.2009.05.019. Cell Stem Cell. 2009. PMID: 19664991 Free article.

10

Anti-DLL4 has broad spectrum activity in pancreatic cancer dependent on targeting DLL4-Notch signaling in both tumor and vasculature cells.

Yen WC, Fischer MM, Hynes M, Wu J, Kim E, Beviglia L, Yeung VP, Song X, Kapoun AM, Lewicki J, Gurney A, Simeone DM, Hoey T. Yen WC, et al. Clin Cancer Res. 2012 Oct 1;18(19):5374-86. doi: 10.1158/1078-0432.CCR-12-0736. Epub 2012 Sep 5. Clin Cancer Res. 2012. PMID: 22952347

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