Chan DA - Search Results

1

Coordinate regulation of the oxygen-dependent degradation domains of hypoxia-inducible factor 1 alpha.

Chan DA, Sutphin PD, Yen SE, Giaccia AJ. Chan DA, et al. Mol Cell Biol. 2005 Aug;25(15):6415-26. doi: 10.1128/MCB.25.15.6415-6426.2005. Mol Cell Biol. 2005. PMID: 16024780 Free PMC article.

2

PHD2 in tumour angiogenesis.

Chan DA, Giaccia AJ. Chan DA, et al. Br J Cancer. 2010 Jun 29;103(1):1-5. doi: 10.1038/sj.bjc.6605682. Epub 2010 May 11. Br J Cancer. 2010. PMID: 20461086 Free PMC article. Review.

3

Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1 alpha enhances hypoxic gene expression and tumor growth.

Krieg AJ, Rankin EB, Chan D, Razorenova O, Fernandez S, Giaccia AJ. Krieg AJ, et al. Mol Cell Biol. 2010 Jan;30(1):344-53. doi: 10.1128/MCB.00444-09. Mol Cell Biol. 2010. PMID: 19858293 Free PMC article.

4

Role of prolyl hydroxylation in oncogenically stabilized hypoxia-inducible factor-1alpha.

Chan DA, Sutphin PD, Denko NC, Giaccia AJ. Chan DA, et al. J Biol Chem. 2002 Oct 18;277(42):40112-7. doi: 10.1074/jbc.M206922200. Epub 2002 Aug 16. J Biol Chem. 2002. PMID: 12186875 Free article.

5

Dead cells don't form tumors: HIF-dependent cytotoxins.

Sutphin PD, Chan DA, Giaccia AJ. Sutphin PD, et al. Among authors: chan da. Cell Cycle. 2004 Feb;3(2):160-3. Cell Cycle. 2004. PMID: 14712081 Review.

6

OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha.

Baek JH, Mahon PC, Oh J, Kelly B, Krishnamachary B, Pearson M, Chan DA, Giaccia AJ, Semenza GL. Baek JH, et al. Among authors: chan da. Mol Cell. 2005 Feb 18;17(4):503-12. doi: 10.1016/j.molcel.2005.01.011. Mol Cell. 2005. PMID: 15721254 Free article.

7

Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro.

Pan Y, Mansfield KD, Bertozzi CC, Rudenko V, Chan DA, Giaccia AJ, Simon MC. Pan Y, et al. Among authors: chan da. Mol Cell Biol. 2007 Feb;27(3):912-25. doi: 10.1128/MCB.01223-06. Epub 2006 Nov 13. Mol Cell Biol. 2007. PMID: 17101781 Free PMC article.

8

Energy regulation: HIF MXIes it up with the C-MYC powerhouse.

Sutphin PD, Giaccia AJ, Chan DA. Sutphin PD, et al. Among authors: chan da. Dev Cell. 2007 Jun;12(6):845-6. doi: 10.1016/j.devcel.2007.05.006. Dev Cell. 2007. PMID: 17543856 Free article. Review.

9

Oxygen sensitivity of reporter genes: implications for preclinical imaging of tumor hypoxia.

Cecic I, Chan DA, Sutphin PD, Ray P, Gambhir SS, Giaccia AJ, Graves EE. Cecic I, et al. Among authors: chan da. Mol Imaging. 2007 Jul-Aug;6(4):219-28. Mol Imaging. 2007. PMID: 17711777

10

Hypoxia-inducible factor-1alpha stabilization in nonhypoxic conditions: role of oxidation and intracellular ascorbate depletion.

Pagé EL, Chan DA, Giaccia AJ, Levine M, Richard DE. Pagé EL, et al. Among authors: chan da. Mol Biol Cell. 2008 Jan;19(1):86-94. doi: 10.1091/mbc.e07-06-0612. Epub 2007 Oct 17. Mol Biol Cell. 2008. PMID: 17942596 Free PMC article.

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